3-phosphoinositide dependent protein kinase 1
Kinase structure
Kinase:PDPK1 (PDK1)
Family:PDK1
Group:AGC
Species:HUMAN
IUPHAR/BPS ID:1519
PDB:3ORX
sc-PDB:
KIDFamMap:Search
Release date:2011-03-23
PubMed: 21430264
Chain:G
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The orthosteric binding pocket


More entries for 3ORX
3ORXChain: A
3ORXChain: B
3ORXChain: C
3ORXChain: D
3ORXChain: E
3ORXChain: F
3ORXChain: H


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):59.9° (17.4Å)
G-rich loop rotation:45.4°
Quality Score:8.2
Resolution:2.2 Å
Missing Residues:0
Missing Atoms:18

Allosteric Ligand
Allosteric ligand:1F8
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:KILGEGSFSTVVLYAIKILYVTRERDVMSRLDPFFVKLYFTYFGLSYAKNGELLKYIRKYLHGKGIIHRDLKPENILLITDFGTA
Sequence structure:KILGEGSFSTVVLYAIKILYVTRERDVMSRLDPFFVKLYFCYFGLSYAKNGELLKYIRKYLHGKGIIHRDLKPENILLITDFGTA