Fibroblast growth factor receptor 1
Kinase structure
Kinase:FGFR1
Family:FGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1808
PDB:4UWY
sc-PDB:
KIDFamMap:Search
Release date:2015-02-25
PubMed: 26097890
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 4UWY
4UWYAlternative model: AChain: B
4UWYAlternative model: BChain: A
4UWYAlternative model: BChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:6
Resolution:2.3 Å
Missing Residues:5
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I4
I5
I6
Ligand
No
No
No
No
Protein
Yes
Yes
Yes
No

Pocket alignment
Uniprot sequence:KPLGEGCFGQVVLVAVKMLDLISEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLQAYLASKKCIHRDLAARNVLVIADFGLA
Sequence structure:KPLG_____QVVLVAVKMLDLISEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLQAYLASKKCIHRDLAARNVLVIADFGLA