Fibroblast growth factor receptor 1
Kinase structure
Kinase:FGFR1
Family:FGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1808
PDB:1FGK
sc-PDB:
KIDFamMap:Search
Release date:1997-07-23
PubMed: 8752212
Chain:B
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 1FGK
1FGKAlternative model: AChain: A
1FGKAlternative model: BChain: A
1FGKAlternative model: BChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):62.5° (18.3Å)
G-rich loop rotation:42°
Quality Score:8.2
Resolution:2 Å
Missing Residues:0
Missing Atoms:18
Ligand binding mode
Waters
Cluster
I3
I4
I5
I6
Ligand
No
No
No
No
Protein
Yes
Yes
Yes
No

Pocket alignment
Uniprot sequence:KPLGEGCFGQVVLVAVKMLDLISEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLQAYLASKKCIHRDLAARNVLVIADFGLA
Sequence structure:KPLGEGAFGQVVLVAVKMLDLISEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLQAYLASKKCIHRDLAARNVLVIADFGLA