Fibroblast growth factor receptor 1
Kinase structure
Kinase:FGFR1
Family:FGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1808
PDB:3KY2
sc-PDB:
KIDFamMap:Search
Release date:2010-03-02
PubMed: 20133753
Chain:A
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The orthosteric binding pocket


More entries for 3KY2
3KY2Chain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):60.9° (17.8Å)
G-rich loop rotation:37.9°
Quality Score:7.2
Resolution:2.7 Å
Missing Residues:2
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I4
I5
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:KPLGEGCFGQVVLVAVKMLDLISEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLQAYLASKKCIHRDLAARNVLVIADFGLA
Sequence structure:KPLGEG__GQVVLVAVKMLDLISEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLQAYLASKKCIHRDLAARNVLVIADFGLA