Mitogen-activated protein kinase 8
Kinase structure
Kinase:MAPK8 (JNK1)
Family:MAPK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1496
PDB:3O2M
sc-PDB:
KIDFamMap:Search
Release date:2011-01-12
PubMed: 21090814
Chain:B
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The orthosteric binding pocket


More entries for 3O2M
3O2MChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):47.7° (14.1Å)
G-rich loop rotation:49°
Quality Score:8
Resolution:2.7 Å
Missing Residues:0
Missing Atoms:0

Allosteric Ligand
Allosteric ligand:46A
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:KPIGSGAQGIVCAVAIKKLRAYRELVLMKCVNKNIIGLLNVYIVMELMD-ANLCQVIQMHLHSAGIIHRDLKPSNIVVILDFGLA
Sequence structure:KPIGSGAQGIVCAVAIKKLRAYRELVLMKCVNKNIIGLLNVYIVMELMD_ANLCQVIQMHLHSAGIIHRDLKPSNIVVILDFGLA