PDB-code
Search results (69 entries covering 37 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | MAPK8 (JNK1) | MAPK | CMGC | 3o2m | B | - | Human | Show |  | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xrw | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vul | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | D | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | C | B | - | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | C | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4l7f | A | B | n-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 2g01 | A | 6-chloro-9-hydroxy-1,3-dimethyl-1,9-dihydro-4h-pyrazolo[3,4-b]quinolin-4-one | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 3o17 | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 2no3 | B | 2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamide | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 3v3v | A | 3,5,6,7-tetrahydroxy-2-(3,4-dihydroxyphenyl)-4h-chromen-4-one | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | F | B | - | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vug | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4awi | A | B | n-(1,1-dioxidotetrahydro-2h-thiopyran-4-yl)-4-[2-(1-methylethyl)-1h-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 6zr5 | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | C | A | - | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 1ukh | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 2h96 | A | 5-cyano-n-(2,5-dimethoxybenzyl)-6-ethoxypyridine-2-carboxamide | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4awi | A | A | n-(1,1-dioxidotetrahydro-2h-thiopyran-4-yl)-4-[2-(1-methylethyl)-1h-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 6f5e | B | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 2gmx | A | n-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-bromo-2,5-dimethoxyphenyl)acetamide | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4qtd | A | A | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4g1w | A | methyl 7-fluoro-3-{4-[(2-hydroxyethyl)sulfonyl]benzyl}-4-oxo-1-phenyl-1,4-dihydroquinoline-2-carboxylate | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xs0 | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 2gmx | B | n-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-bromo-2,5-dimethoxyphenyl)acetamide | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 1uki | A | 2,6-dihydroanthra/1,9-cd/pyrazol-6-one | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vuh | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 2g01 | B | 6-chloro-9-hydroxy-1,3-dimethyl-1,9-dihydro-4h-pyrazolo[3,4-b]quinolin-4-one | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 5lw1 | H | adenosine | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | B | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | E | A | - | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4qtd | A | B | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 6zr5 | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4hys | A | trans-4-{[4-(1h-indazol-1-yl)pyrimidin-2-yl]amino}cyclohexanol | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4izy | A | trans-4-[(4-{4-[4-(methylsulfonyl)piperidin-1-yl]-1h-indol-1-yl}pyrimidin-2-yl)amino]cyclohexanol | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vui | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xrw | A | C | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vud | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 3elj | A | B | 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | B | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 2no3 | A | 2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamide | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 3o17 | B | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | A | B | - | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 3o2m | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | D | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4l7f | A | C | n-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vuk | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 2h96 | B | 5-cyano-n-(2,5-dimethoxybenzyl)-6-ethoxypyridine-2-carboxamide | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | C | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 8x5m | A | B | 3-[4-(dimethylamino)butanoylamino]-~{n}-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 3pze | A | 3-(carbamoylamino)-5-phenylthiophene-2-carboxamide | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 8pt9 | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 8pt8 | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 8pta | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 8x5m | A | A | 3-[4-(dimethylamino)butanoylamino]-~{n}-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 5lw1 | B | adenosine | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | A | A | - | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4hyu | A | trans-4-[(4-{4-[3-(methylsulfonyl)propoxy]-1h-indazol-1-yl}pyrimidin-2-yl)amino]cyclohexanol | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4l7f | A | A | n-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4e73 | A | B | methyl 3-(4-{[(1r,2s,3s,5s,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 5lw1 | E | adenosine | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 4e73 | A | A | methyl 3-(4-{[(1r,2s,3s,5s,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | F | A | - | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xrw | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vum | A | - | Human | Show | | |
| MAPK8 (JNK1) | MAPK | CMGC | 3elj | A | A | 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide | Human | Show | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | E | B | - | Human | Show | |
