Cyclin-dependent kinase 12
Kinase structure
Kinase:CDK12 (CRK7)
Family:CDK
Group:CMGC
Species:HUMAN
PDB:4UN0
sc-PDB:
KIDFamMap:Search
Release date:2014-06-04
PubMed: 26597175
Chain:C
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The orthosteric binding pocket


More entries for 4UN0
4UN0Chain: D


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):61.8° (17.9Å)
G-rich loop rotation:70.3°
Quality Score:8
Resolution:3.15 Å
Missing Residues:0
Missing Atoms:29

Pocket alignment
Uniprot sequence:GIIGEGTYGQVYKVALKKVTAIREIKILRQLIRSVVNMKEIYLVFEYMD-HDLMGLLESYCHKKNFLHRDIKCSNILLLADFGLA
Sequence structure:GIIGEGTYGQVYKVALKKVTAIREIKILRQLIRSVVNMKEIYLVFEYMD_HDLMGLLESYCHKKNFLHRDIKCSNILLLADFGLA