PDB-code
| Kinase structure | |
| Kinase: | MAPK14 (p38a) |
| Family: | MAPK |
| Group: | CMGC |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 1499 |
| PDB: | 4EHV |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2012-12-05 |
| PubMed: | 23247173 |
| Chain: | A |
| (Alternate) Model: | A |
| More entries for 4EHV | |||||
| 4EHV | Alternative model: | B | Chain: | A | |
| Structural information | |
| DFG conformation: | out-like |
| αC-helix conformation: | in |
| G-rich loop angle (distance): | 55.6° (16.1Å) |
| G-rich loop rotation: | 53.9° |
| Quality Score: | 9 |
| Resolution: | 1.6 Å |
| Missing Residues: | 1 |
| Missing Atoms: | 2 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I3 I6 | Ligand No No | Protein Yes Yes | ||
| Allosteric Ligand | |
| Allosteric ligand: | 0SJ |
 | |
| Pocket alignment | |
| Uniprot sequence: | SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG-ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGLA |
| Sequence structure: | SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG_ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGL_ |
