Fibroblast growth factor receptor 2
Kinase structure
Kinase:FGFR2
Family:FGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1809
PDB:2PSQ
sc-PDB:
KIDFamMap:Search
Release date:2007-09-25
PubMed: 17803937
Chain:A
Click to open a 3D viewer
The orthosteric binding pocket


More entries for 2PSQ
2PSQChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):61.1° (17.6Å)
G-rich loop rotation:13.5°
Quality Score:8
Resolution:2.4 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I5
I8
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:KPLGEGCFGQVVMVAVKMLDLVSEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLRAYLASQKCIHRDLAARNVLVIADFGLA
Sequence structure:KPLGEGCFGQVVMVAVKMLDLVSEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLRAYLASQKCIHRDLAARNVLVIADFGLA