Search results (116 entries covering 37 PDB structures)

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#	Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	File
	FGFR2	FGFR	TK	2pvy	C		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	C	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	D	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	B	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2psq	A		-	Human	Show
	FGFR2	FGFR	TK	4j97	A	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pz5	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	A	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	8e1x	A		(5m)-n-methyl-5-{(6m,8s)-5-{[(3s)-oxolan-3-yl]amino}-6-[1-(propan-2-yl)-1h-pyrazol-3-yl]pyrazolo[1,5-a]pyrimidin-3-yl}pyridine-3-carboxamide	Human	Show
	FGFR2	FGFR	TK	2py3	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	3cly	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	7ozy	A	B	4-[3-(4-piperazin-4-ium-1-ylphenyl)-1h-indazol-6-yl]phenol	Human	Show
	FGFR2	FGFR	TK	7kie	B	A	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	Show
	FGFR2	FGFR	TK	6agx	C	B	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	6agx	A	B	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	5uhn	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	7ozy	A	A	4-[3-(4-piperazin-4-ium-1-ylphenyl)-1h-indazol-6-yl]phenol	Human	Show
	FGFR2	FGFR	TK	4j99	A	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ui0	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ugl	A	B	phosphoaminophosphonic acid-adenylate ester	Human	Show
	FGFR2	FGFR	TK	6agx	D	B	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	2pzr	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	8swe	A	B	n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide	Human	Show
	FGFR2	FGFR	TK	4j95	D	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j97	D	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pvf	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5uhn	A	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ugx	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	1gjo	A		-	Human	Show
	FGFR2	FGFR	TK	7kie	B	B	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	Show
	FGFR2	FGFR	TK	4j96	A	B	-	Human	Show
	FGFR2	FGFR	TK	6agx	C	A	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	4j95	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pzp	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j95	A	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	7kia	A	B	1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-one	Human	Show
	FGFR2	FGFR	TK	5ugx	A	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6v6q	C		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6lvl	A		n-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide	Human	Show
	FGFR2	FGFR	TK	6lvl	B		n-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide	Human	Show
	FGFR2	FGFR	TK	4j97	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6agx	B	A	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	4j95	C	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	C	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j98	A	B	-	Human	Show
	FGFR2	FGFR	TK	4j99	D	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j95	C	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j97	D	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j95	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pwl	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j98	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	8w38	A	B	1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one	Human	Show
	FGFR2	FGFR	TK	6agx	B	B	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	4j97	C	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6lvk	B		n-ethyl-2-[[4-[[4-(4-methylpiperazin-1-yl)-3-(2-morpholin-4-ylethoxy)phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide	Human	Show
	FGFR2	FGFR	TK	5ugl	B	A	phosphoaminophosphonic acid-adenylate ester	Human	Show
	FGFR2	FGFR	TK	1oec	A		4-aryl-2-phenylamino pyrimidine	Human	Show
	FGFR2	FGFR	TK	4j99	D	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6v6q	D		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	A	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ui0	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6v6q	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pz5	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	7kia	B	A	1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-one	Human	Show
	FGFR2	FGFR	TK	6lvk	A		n-ethyl-2-[[4-[[4-(4-methylpiperazin-1-yl)-3-(2-morpholin-4-ylethoxy)phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide	Human	Show
	FGFR2	FGFR	TK	4j95	A	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j97	B	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j97	C	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j96	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j97	A	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5eg3	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j98	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pvy	D		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5uhn	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ugx	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6v6q	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pzp	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2psq	B		-	Human	Show
	FGFR2	FGFR	TK	2q0b	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	2pwl	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	C	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	7kia	A	A	1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-one	Human	Show
	FGFR2	FGFR	TK	2py3	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j95	D	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	6agx	D	A	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	5ugl	A	A	phosphoaminophosphonic acid-adenylate ester	Human	Show
	FGFR2	FGFR	TK	2q0b	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5uhn	A	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j97	A	C	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	3b2t	A		5'-o-[(s)-hydroxy{[(s)-hydroxy(methyl)phosphoryl]oxy}phosphoryl]adenosine	Human	Show
	FGFR2	FGFR	TK	3b2t	B		5'-o-[(s)-hydroxy{[(s)-hydroxy(methyl)phosphoryl]oxy}phosphoryl]adenosine	Human	Show
	FGFR2	FGFR	TK	4j97	D	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	7kia	B	B	1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-one	Human	Show
	FGFR2	FGFR	TK	6agx	A	A	ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetate	Human	Show
	FGFR2	FGFR	TK	4j97	C	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ugl	B	B	phosphoaminophosphonic acid-adenylate ester	Human	Show
	FGFR2	FGFR	TK	8u1f	A		n-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7h-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamide	Human	Show
	FGFR2	FGFR	TK	7kie	A	B	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	Show
	FGFR2	FGFR	TK	2pvy	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	7kie	A	A	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	Show
	FGFR2	FGFR	TK	4j96	A	A	-	Human	Show
	FGFR2	FGFR	TK	2pvy	A		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j99	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ugx	A	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	8swe	A	A	n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide	Human	Show
	FGFR2	FGFR	TK	2pzr	B		phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	4j97	B	B	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	5ui0	A	B	-	Human	Show
	FGFR2	FGFR	TK	4j96	B	A	phosphomethylphosphonic acid adenylate ester	Human	Show
	FGFR2	FGFR	TK	8h75	A		4-[9-(2-chlorophenyl)-6-methyl-2,4,5,8,12-pentazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3,6,8,11,13-hexaen-13-yl]morpholine	Human	Show
	FGFR2	FGFR	TK	3ri1	B		(6s)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine	Human	Show
	FGFR2	FGFR	TK	5ui0	A	A	-	Human	Show
	FGFR2	FGFR	TK	8stg	A		n-{4-[(5p)-4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}-2-methylprop-2-enamide	Human	Show
	FGFR2	FGFR	TK	3ri1	A		(6s)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine	Human	Show
	FGFR2	FGFR	TK	4j98	A	A	-	Human	Show

Division of Medicinal Chemistry - Vrije Universiteit Amsterdam