Mitogen-activated protein kinase 14
Kinase structure
Kinase:MAPK14 (p38a)
Family:MAPK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1499
PDB:3NEW
sc-PDB:
KIDFamMap:Search
Release date:2010-12-01
PubMed: 21090814
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 3NEW
3NEWAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):59.8° (18.2Å)
G-rich loop rotation:43.8°
Quality Score:8.7
Resolution:2.51 Å
Missing Residues:0
Missing Atoms:13

Allosteric Ligand
Allosteric ligand:3NE
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG-ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGLA
Sequence structure:SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG_ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGLA