TEK receptor tyrosine kinase
Kinase structure
Kinase:TEK (TIE2)
Family:Tie
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1842
PDB:1FVR
sc-PDB:
KIDFamMap:Search
Release date:2001-09-20
PubMed: 11080633
Chain:A
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The orthosteric binding pocket


More entries for 1FVR
1FVRChain: B


Structural information
DFG conformation:out-like
αC-helix conformation:out
G-rich loop angle (distance):38.4° (11.9Å)
G-rich loop rotation:79.6°
Quality Score:8
Resolution:2.2 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I2
I7
Ligand
No
No
No
Protein
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:DVIGEGNFGQVLKAAIKRMDFAGELEVLCKLGPNIINLLGAYLAIEYAPHGNLLDFLRKYLSQKQFIHRDLAARNILVIADFGLS
Sequence structure:DVIGEGNFGQVLKAAIKRMDFAGELEVLCKLGPNIINLLGAYLAIEYAPHGNLLDFLRKYLSQKQFIHRDLAARNILVIADFGLS