Germ cell associated 2 (haspin)
Kinase structure
Kinase:HASPIN (Haspin)
Family:Haspin
Group:Other
Species:HUMAN
IUPHAR/BPS ID:2028
PDB:5HTB
sc-PDB:
KIDFamMap:Search
Release date:2016-05-11
PubMed: 27139824
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 5HTB
5HTBAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):52.3° (15.8Å)
G-rich loop rotation:52.9°
Quality Score:8
Resolution:1.7 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I4
I5
I7
I10
Ligand
No
No
No
No
No
Protein
Yes
Yes
Yes
No
Yes

Pocket alignment
Uniprot sequence:EKIGEGVFGEVFQVAIKIIEILPEIIISKELSEGFIGLNSVVLEFEFGG-IDLEQMRTKAEASLRFEHRDLHWGNVLLIIDYTLS
Sequence structure:EKIGEGVFGEVFQVAIKIIEILPEIIISKELSEGFIGLNSVVLEFEFGG_IDLEQMRTKAEASLRFEHRDLHWGNVLLIIDYTLS