B-Raf proto-oncogene, serine/threonine kinase
Kinase structure
Kinase:BRAF
Family:RAF
Group:TKL
Species:HUMAN
IUPHAR/BPS ID:1943
PDB:5JSM
sc-PDB:
KIDFamMap:Search
Release date:2016-09-14
PubMed: 27571413
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 5JSM
5JSMAlternative model: AChain: A
5JSMAlternative model: AChain: B
5JSMAlternative model: AChain: C
5JSMAlternative model: AChain: D
5JSMAlternative model: BChain: B
5JSMAlternative model: BChain: C
5JSMAlternative model: BChain: D


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):45.4° (13.3Å)
G-rich loop rotation:63.2°
Quality Score:9.2
Resolution:2.19 Å
Missing Residues:0
Missing Atoms:8

Allosteric Ligand
Allosteric ligand:BEN
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:QRIGSGSFGTVYKVAVKMLAFKNEVGVLRKTRVNILLFMGYAIVTQWCEGSSLYHHLHIYLHAKSIIHRDLKSNNIFLIGDFGLA
Sequence structure:QRIGSGSFGTVYKVAVKMLAFKNEVGVLRKTRVNILLFMGYAIVTQWCEGSSLYHHLHAYLHAKSIIHRDLKSNNIFLIGDFGLA