Fibroblast growth factor receptor 2
Kinase structure
Kinase:FGFR2
Family:FGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1809
PDB:5UI0
sc-PDB:
KIDFamMap:Search
Release date:2017-02-22
PubMed: 28166054
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 5UI0
5UI0Alternative model: AChain: A
5UI0Alternative model: AChain: B
5UI0Alternative model: BChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):52.7° (15.9Å)
G-rich loop rotation:40.4°
Quality Score:8
Resolution:2.05 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I3
Ligand
No
Protein
No

Pocket alignment
Uniprot sequence:KPLGEGCFGQVVMVAVKMLDLVSEMEMMKMIGKNIINLLGAYVIVEYASKGNLREYLRAYLASQKCIHRDLAARNVLVIADFGLA
Sequence structure:KPLGEGAFGQVVMVAVKMLDLVSEMEMMKMIGKNIINLLGAYVIVAYASKGNLREYLRAYLASQKCIHRDLAARNVLVIADFGLA