Mitogen-activated protein kinase 14
Kinase structure
Kinase:MAPK14 (p38a)
Family:MAPK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1499
PDB:5N64
sc-PDB:
KIDFamMap:Search
Release date:2017-09-20
PubMed: 28892510
Chain:A
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The orthosteric binding pocket
Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:5.2
Resolution:2.4 Å
Missing Residues:7
Missing Atoms:0

Allosteric Ligand
Allosteric ligand:8OH
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG-ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGLA
Sequence structure:SPVGSG___SVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG_ADLNNILT_YIHSADIIHRDLKPSNLAVILDF___