PDB-code
Browse kinase entries (page 126 of 282)
First 122 123 124 PreviousLast130 129 128 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | FGFR2 | FGFR | TK | 8h75 | A | 4-[9-(2-chlorophenyl)-6-methyl-2,4,5,8,12-pentazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3,6,8,11,13-hexaen-13-yl]morpholine | Human | Show |  | |
| FGFR2 | FGFR | TK | 8stg | A | n-{4-[(5p)-4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}-2-methylprop-2-enamide | Human | Show | | |
| FGFR2 | FGFR | TK | 8swe | A | A | n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide | Human | Show | |
| FGFR2 | FGFR | TK | 8swe | A | B | n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide | Human | Show | |
| FGFR2 | FGFR | TK | 8u1f | A | n-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7h-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamide | Human | Show | | |
| FGFR2 | FGFR | TK | 8w38 | A | B | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | Show | |
| FGFR3 | FGFR | TK | 4k33 | A | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| FGFR3 | FGFR | TK | 4k33 | A | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| FGFR3 | FGFR | TK | 6lvm | A | 2-[[5-[2-(3,5-dimethoxyphenyl)ethyl]-2-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]pyrimidin-4-yl]amino]-n-ethyl-benzenesulfonamide | Human | Show | | |
| FGFR3 | FGFR | TK | 6pnx | A | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| FGFR3 | FGFR | TK | 6pnx | A | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| FGFR3 | FGFR | TK | 6pnx | B | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| FGFR3 | FGFR | TK | 6pnx | B | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| FGFR3 | FGFR | TK | 7dhl | A | 5-[2-(3,5-dimethoxyphenyl)ethyl]-n-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine | Human | Show | | |
| FGFR3 | FGFR | TK | 8udt | A | 3-[(1-cyclopropyl-4,6-difluoro-1h-benzimidazol-5-yl)ethynyl]-1-[(3r,5r)-5-(methoxymethyl)-1-propanoylpyrrolidin-3-yl]-5-(methylamino)-1h-pyrazole-4-carboxamide | Human | Show | | |
| FGFR3 | FGFR | TK | 8udu | A | A | 3-[(6-chloro-1-cyclopropyl-1h-benzimidazol-5-yl)ethynyl]-1-[(3s,5s)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)-1h-pyrazole-4-carboxamide | Human | Show | |
| FGFR3 | FGFR | TK | 8udu | A | B | 3-[(6-chloro-1-cyclopropyl-1h-benzimidazol-5-yl)ethynyl]-1-[(3s,5s)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)-1h-pyrazole-4-carboxamide | Human | Show | |
| FGFR3 | FGFR | TK | 8udv | A | 3-[(6-chloro-1-cyclopropyl-1h-benzimidazol-5-yl)ethynyl]-1-[(3s,5s)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)-1h-pyrazole-4-carboxamide | Human | Show | | |
| FGFR4 | FGFR | TK | 4qq5 | A | n-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2h)-yl]methyl}phenyl)propanamide | Human | Show | | |
| FGFR4 | FGFR | TK | 4qqc | A | A | n-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2h)-yl]methyl}phenyl)propanamide | Human | Show | |
| FGFR4 | FGFR | TK | 4qqc | A | B | n-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2h)-yl]methyl}phenyl)propanamide | Human | Show | |
| FGFR4 | FGFR | TK | 4qqj | A | - | Human | Show | | |
| FGFR4 | FGFR | TK | 4qqt | A | - | Human | Show | | |
| FGFR4 | FGFR | TK | 4qrc | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | | |
| FGFR4 | FGFR | TK | 4r6v | A | n-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide | Human | Show | | |
| FGFR4 | FGFR | TK | 4tye | A | - | Human | Show | | |
| FGFR4 | FGFR | TK | 4tyg | A | A | - | Human | Show | |
| FGFR4 | FGFR | TK | 4tyg | A | B | - | Human | Show | |
| FGFR4 | FGFR | TK | 4tyi | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | Show | | |
| FGFR4 | FGFR | TK | 4tyj | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | | |
| FGFR4 | FGFR | TK | 4uxq | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | | |
| FGFR4 | FGFR | TK | 4xcu | A | A | n-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)prop-2-enamide | Human | Show | |
| FGFR4 | FGFR | TK | 4xcu | A | B | n-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)prop-2-enamide | Human | Show | |
| FGFR4 | FGFR | TK | 5jkg | A | 2-[4-[e-2-[5-[(1r)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1h-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol | Human | Show | | |
| FGFR4 | FGFR | TK | 5nud | A | 3-chloranyl-~{n}-(3-nitropyridin-2-yl)-5-(trifluoromethyl)pyridin-2-amine | Human | Show | | |
| FGFR4 | FGFR | TK | 5nud | B | 3-chloranyl-~{n}-(3-nitropyridin-2-yl)-5-(trifluoromethyl)pyridin-2-amine | Human | Show | | |
| FGFR4 | FGFR | TK | 5nwz | A | ~{n}-[3-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-5-yl]-2-(propanoylamino)benzamide | Human | Show | | |
| FGFR4 | FGFR | TK | 5nwz | B | ~{n}-[3-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-5-yl]-2-(propanoylamino)benzamide | Human | Show | | |
| FGFR4 | FGFR | TK | 5xff | A | 2-[4-[e-2-[5-[(1r)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1h-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol | Human | Show | | |
| FGFR4 | FGFR | TK | 5xfj | A | 2-[4-[e-2-[5-[(1r)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1h-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol | Human | Show | | |
| FGFR4 | FGFR | TK | 6iuo | A | n-({4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2h-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}methyl)prop-2-enamide | Human | Show | | |
| FGFR4 | FGFR | TK | 6iup | A | A | n-{4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2h-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}prop-2-enamide | Human | Show | |
| FGFR4 | FGFR | TK | 6iup | A | B | n-{4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2h-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}prop-2-enamide | Human | Show | |
| FGFR4 | FGFR | TK | 6jpe | A | n-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide | Human | Show | | |
| FGFR4 | FGFR | TK | 6jpj | A | n-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2h-1,8-naphthyridine-1-carboxamide | Human | Show | | |
| FGFR4 | FGFR | TK | 6nvg | A | n-[3,5-dichloro-2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)phenyl]propanamide | Human | Show | | |
| FGFR4 | FGFR | TK | 6nvh | A | A | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | Show | |
| FGFR4 | FGFR | TK | 6nvh | A | B | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | Show | |
| FGFR4 | FGFR | TK | 6nvi | A | A | n-[3-chloro-2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-5-fluorophenyl]propanamide | Human | Show | |
| FGFR4 | FGFR | TK | 6nvi | A | B | n-[3-chloro-2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-5-fluorophenyl]propanamide | Human | Show | |
