PDB-code
Browse kinase entries (page 141 of 282)
First 137 138 139 PreviousLast145 144 143 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | IRAK4 | IRAK | TKL | 4ztn | A | A | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show |  |
| IRAK4 | IRAK | TKL | 4ztn | A | B | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztn | B | A | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztn | B | B | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztn | C | A | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztn | C | B | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztn | D | A | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztn | D | B | 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3r)-piperidin-3-ylamino]pyrimidin-4(3h)-one | Human | Show | |
| IRAK4 | IRAK | TKL | 5k72 | A | ~{n}4,~{n}4-dimethyl-~{n}1-[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]cyclohexane-1,4-diamine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k72 | B | ~{n}4,~{n}4-dimethyl-~{n}1-[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]cyclohexane-1,4-diamine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k72 | C | ~{n}4,~{n}4-dimethyl-~{n}1-[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]cyclohexane-1,4-diamine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k72 | D | ~{n}4,~{n}4-dimethyl-~{n}1-[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]cyclohexane-1,4-diamine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k75 | A | A | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k75 | A | B | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k75 | B | A | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k75 | B | B | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k75 | C | A | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k75 | C | B | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k75 | D | A | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k75 | D | B | ~{n}1-(7,8-dihydro-6~{h}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{n}4,~{n}4-dimethyl-cyclohexane-1,4-diamine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k76 | A | A | ~{n}-(4-morpholin-4-ylcyclohexyl)-5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k76 | A | B | ~{n}-(4-morpholin-4-ylcyclohexyl)-5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k76 | B | A | ~{n}-(4-morpholin-4-ylcyclohexyl)-5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k76 | B | B | ~{n}-(4-morpholin-4-ylcyclohexyl)-5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | |
| IRAK4 | IRAK | TKL | 5k7g | A | (3~{a}~{s},7~{a}~{r})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k7g | B | (3~{a}~{s},7~{a}~{r})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k7g | C | (3~{a}~{s},7~{a}~{r})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k7g | D | (3~{a}~{s},7~{a}~{r})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k7i | A | (3~{a}~{r},7~{a}~{s})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 5k7i | B | (3~{a}~{r},7~{a}~{s})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 5kx7 | A | - | Human | Show | | |
| IRAK4 | IRAK | TKL | 5kx7 | B | ~{n}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-6-(1-methylpyrazol-4-yl)pyridine-2-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5kx8 | A | ~{n}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-5-piperazin-1-yl-pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5kx8 | B | ~{n}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-5-piperazin-1-yl-pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5kx8 | C | ~{n}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-5-piperazin-1-yl-pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5kx8 | D | ~{n}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-5-piperazin-1-yl-pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1s | A | 5-[3-(3,5-dimethylphenyl)-4-[4-(methylamino)butyl]quinolin-6-yl]pyridin-3-ol | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1s | B | 5-[3-(3,5-dimethylphenyl)-4-[4-(methylamino)butyl]quinolin-6-yl]pyridin-3-ol | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1s | C | 5-[3-(3,5-dimethylphenyl)-4-[4-(methylamino)butyl]quinolin-6-yl]pyridin-3-ol | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1s | D | 5-[3-(3,5-dimethylphenyl)-4-[4-(methylamino)butyl]quinolin-6-yl]pyridin-3-ol | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1t | A | ~{n},~{n}-dimethyl-4-(6-nitroquinazolin-4-yl)oxy-cyclohexan-1-amine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1t | B | ~{n},~{n}-dimethyl-4-(6-nitroquinazolin-4-yl)oxy-cyclohexan-1-amine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1t | C | ~{n},~{n}-dimethyl-4-(6-nitroquinazolin-4-yl)oxy-cyclohexan-1-amine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5t1t | D | ~{n},~{n}-dimethyl-4-(6-nitroquinazolin-4-yl)oxy-cyclohexan-1-amine | Human | Show | | |
| IRAK4 | IRAK | TKL | 5uiq | A | A | 2-[(propan-2-yl)oxy]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiq | A | B | 2-[(propan-2-yl)oxy]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiq | B | A | 2-[(propan-2-yl)oxy]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiq | B | B | 2-[(propan-2-yl)oxy]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiq | C | A | 2-[(propan-2-yl)oxy]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiq | C | B | 2-[(propan-2-yl)oxy]benzamide | Human | Show | |
