PDB-code
Browse kinase entries (page 16 of 282)
First 12 13 14 PreviousLast20 19 18 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | AURKA (AurA) | Aur | Other | 2w1d | A | 2-(1h-pyrazol-3-yl)-1h-benzimidazole | Human | Show |  | |
| AURKA (AurA) | Aur | Other | 2w1e | A | 4-[(2-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-3-yl}-1h-benzimidazol-5-yl)methyl]morpholin-4-ium | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2w1f | A | n-[3-(1h-benzimidazol-2-yl)-1h-pyrazol-4-yl]benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2w1g | A | 2-{4-[(cyclopropylcarbamoyl)amino]-1h-pyrazol-3-yl}-6-(morpholin-4-ium-4-ylmethyl)-1h-3,1-benzimidazol-3-ium | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2wqe | A | adenosine-5'-diphosphate | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2wtv | A | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtv | A | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtv | B | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtv | B | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtv | C | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtv | C | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtv | D | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtv | D | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | |
| AURKA (AurA) | Aur | Other | 2wtw | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2x6d | A | A | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | Show | |
| AURKA (AurA) | Aur | Other | 2x6d | A | B | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | Show | |
| AURKA (AurA) | Aur | Other | 2x6e | A | 6-bromo-7-{4-[(5-methylisoxazol-3-yl)methyl]piperazin-1-yl}-2-[4-(4-methylpiperazin-1-yl)phenyl]-1h-imidazo[4,5-b]pyridine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2x81 | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2xne | A | 3-chloro-n-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 2xng | A | A | n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide | Human | Show | |
| AURKA (AurA) | Aur | Other | 2xng | A | B | n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide | Human | Show | |
| AURKA (AurA) | Aur | Other | 2xru | A | 3-({[4-(4-methylpiperazin-1-yl)phenyl]carbonyl}amino)-n-[(1r)-1-phenylpropyl]-1h-thieno[3,2-c]pyrazole-5-carboxamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3coh | A | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1h)-one | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3coh | B | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1h)-one | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3e5a | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3efw | A | 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3efw | B | 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3fdn | A | n-[3-(acetylamino)phenyl]-5-{(2e)-2-[(4-methoxyphenyl)methylidene]hydrazino}-3-methyl-1h-pyrazole-4-carboxamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3h0y | A | 2-chloro-n-[4-({5-fluoro-2-[(4-hydroxyphenyl)amino]pyrimidin-4-yl}amino)phenyl]benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3h0z | A | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3h0z | B | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3h0z | C | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3h10 | A | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3h10 | B | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3h10 | D | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3ha6 | A | n~2~-(3,4-dimethoxyphenyl)-n~4~-[2-(2-fluorophenyl)ethyl]-n~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3k5u | A | 2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethanol | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3lau | A | n-[6-(4-hydroxyphenyl)-1h-indazol-3-yl]butanamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3m11 | A | 1-(4-{2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3myg | A | 2-{ethyl[(5-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3nrm | A | n-(3-methylisothiazol-5-yl)-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3o50 | A | n-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3o50 | B | n-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3o51 | A | n-[4-({3-[5-fluoro-2-(methylideneamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-2-(phenylamino)benzamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3p9j | A | 4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2h)-one | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3qbn | A | 5-chloro-n~4~-cyclopropyl-n~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3r21 | A | A | n-(2-aminoethyl)-n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | Show | |
| AURKA (AurA) | Aur | Other | 3r21 | A | B | n-(2-aminoethyl)-n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | Show | |
| AURKA (AurA) | Aur | Other | 3r22 | A | n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | Show | | |
| AURKA (AurA) | Aur | Other | 3unz | A | 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | Show | |
