PDB-code
Browse kinase entries (page 155 of 282)
First 151 152 153 PreviousLast159 158 157 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | JAK2-b | JakB | TK | 5i4n | A | A | adenosine-5'-triphosphate | Human | Show |  |
| JAK2-b | JakB | TK | 5i4n | A | B | adenosine-5'-triphosphate | Human | Show | |
| JAK2-b | JakB | TK | 5usz | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | Show | |
| JAK2-b | JakB | TK | 5usz | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | Show | |
| JAK2-b | JakB | TK | 5ut0 | A | A | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | Show | |
| JAK2-b | JakB | TK | 5ut0 | A | B | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | Show | |
| JAK2-b | JakB | TK | 5ut1 | A | A | (7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-one | Human | Show | |
| JAK2-b | JakB | TK | 5ut1 | A | B | (7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-one | Human | Show | |
| JAK2-b | JakB | TK | 5ut2 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | Show | |
| JAK2-b | JakB | TK | 5ut2 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | Show | |
| JAK2-b | JakB | TK | 5ut3 | A | 5-phenyl-2-ureidothiophene-3-carboxamide | Human | Show | | |
| JAK2-b | JakB | TK | 5ut4 | A | 8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1h-pyrazol-4-yl)quinoxaline | Human | Show | | |
| JAK2-b | JakB | TK | 5ut5 | A | A | n-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide | Human | Show | |
| JAK2-b | JakB | TK | 5ut5 | A | B | n-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide | Human | Show | |
| JAK2-b | JakB | TK | 5ut6 | A | A | 4-({4-amino-6-[3-(hydroxymethyl)-1h-pyrazol-1-yl]pyrimidin-2-yl}amino)benzonitrile | Human | Show | |
| JAK2-b | JakB | TK | 5ut6 | A | B | 4-({4-amino-6-[3-(hydroxymethyl)-1h-pyrazol-1-yl]pyrimidin-2-yl}amino)benzonitrile | Human | Show | |
| JAK2-b | JakB | TK | 5wij | A | 4-{[6-(cyclohexylmethoxy)-7h-purin-2-yl]amino}-n,n-diethylbenzamide | Human | Show | | |
| JAK2-b | JakB | TK | 5wik | B | (7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-one | Human | Show | | |
| JAK2-b | JakB | TK | 5wil | A | 5-(3-fluorophenyl)-n-[(3s)-3-piperidyl]-3-ureido-thiophene-2-carboxamide | Human | Show | | |
| JAK2-b | JakB | TK | 5wim | A | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | Show | | |
| JAK2-b | JakB | TK | 5win | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | Show | | |
| JAK2-b | JakB | TK | 6brw | A | A | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | Show | |
| JAK2-b | JakB | TK | 6brw | A | B | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | Show | |
| JAK2-b | JakB | TK | 6bs0 | A | A | 4-(5-aminopyrazin-2-yl)-1h-pyrrolo[2,3-b]pyridin-6-amine | Human | Show | |
| JAK2-b | JakB | TK | 6bs0 | A | B | 4-(5-aminopyrazin-2-yl)-1h-pyrrolo[2,3-b]pyridin-6-amine | Human | Show | |
| JAK2-b | JakB | TK | 6bss | A | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | Show | | |
| JAK2-b | JakB | TK | 6d2i | A | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | Show | | |
| JAK2-b | JakB | TK | 6d2i | B | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | Show | | |
| JAK2-b | JakB | TK | 6g3c | A | A | 2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7,7-trimethyl-8-(3-methylbutyl)pteridin-6-one | Human | Show | |
| JAK2-b | JakB | TK | 6g3c | A | B | 2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7,7-trimethyl-8-(3-methylbutyl)pteridin-6-one | Human | Show | |
| JAK2-b | JakB | TK | 6g3c | B | A | 2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7,7-trimethyl-8-(3-methylbutyl)pteridin-6-one | Human | Show | |
| JAK2-b | JakB | TK | 6g3c | B | B | 2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7,7-trimethyl-8-(3-methylbutyl)pteridin-6-one | Human | Show | |
| JAK2-b | JakB | TK | 6m9h | A | A | 4-({4-amino-6-[4-(2-hydroxyethyl)-1h-imidazol-1-yl]pyrimidin-2-yl}amino)benzonitrile | Human | Show | |
| JAK2-b | JakB | TK | 6m9h | A | B | 4-({4-amino-6-[4-(2-hydroxyethyl)-1h-imidazol-1-yl]pyrimidin-2-yl}amino)benzonitrile | Human | Show | |
| JAK2-b | JakB | TK | 6oav | A | 5-amino-3-[(4-cyanophenyl)amino]-n-phenyl-1h-1,2,4-triazole-1-carboxamide | Human | Show | | |
| JAK2-b | JakB | TK | 6obb | A | 5-amino-n-phenyl-3-[(4-sulfamoylphenyl)amino]-1h-1,2,4-triazole-1-carboxamide | Human | Show | | |
| JAK2-b | JakB | TK | 6obf | A | [4-({5-amino-3-[(4-sulfamoylphenyl)amino]-1h-1,2,4-triazole-1-carbonyl}amino)phenoxy]acetic acid | Human | Show | | |
| JAK2-b | JakB | TK | 6obl | A | [4-({5-amino-3-[(4-cyanophenyl)amino]-1h-1,2,4-triazole-1-carbonyl}amino)phenoxy]acetic acid | Human | Show | | |
| JAK2-b | JakB | TK | 6occ | A | 2-[4-({5-amino-3-[(4-sulfamoylphenyl)amino]-1h-1,2,4-triazole-1-carbonyl}amino)phenyl]-1,3-oxazole-4-carboxylic acid | Human | Show | | |
| JAK3 | JakA | TK | 1yvj | A | A | 1,2,3,4-tetrahydrogen-staurosporine | Human | Show | |
| JAK3 | JakA | TK | 1yvj | A | B | 1,2,3,4-tetrahydrogen-staurosporine | Human | Show | |
| JAK3 | JakA | TK | 3lxk | A | 3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | Human | Show | | |
| JAK3 | JakA | TK | 3lxl | A | A | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | |
| JAK3 | JakA | TK | 3lxl | A | B | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | |
| JAK3 | JakA | TK | 3pjc | A | 3-(1h-indol-3-yl)-4-[2-(4-oxopiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-4-yl]-1h-pyrrole-2,5-dione | Human | Show | | |
| JAK3 | JakA | TK | 3zc6 | A | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zc6 | A | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zc6 | B | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zc6 | B | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zc6 | C | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
