PDB-code
Browse kinase entries (page 157 of 282)
First 153 154 155 PreviousLast161 160 159 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | JAK3 | JakA | TK | 6da4 | A | (z)-1-{2,2-difluoro-6-[5-(2-methoxyethyl)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]-2,3-dihydro-4h-1,4-benzoxazin-4-yl}methanimine | Human | Show |  | |
| JAK3 | JakA | TK | 6db3 | A | A | [(1s)-1-methyl-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]cyanamide | Human | Show | |
| JAK3 | JakA | TK | 6db3 | A | B | [(1s)-1-methyl-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]cyanamide | Human | Show | |
| JAK3 | JakA | TK | 6db4 | A | A | n-[(1s)-6-(5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | Show | |
| JAK3 | JakA | TK | 6db4 | A | B | n-[(1s)-6-(5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | Show | |
| JAK3 | JakA | TK | 6dud | A | A | n-[(1s)-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | Show | |
| JAK3 | JakA | TK | 6dud | A | B | n-[(1s)-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | Show | |
| JAK3 | JakA | TK | 6gl9 | A | A | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6gl9 | A | B | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6gl9 | B | A | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6gl9 | B | B | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6gla | A | A | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6gla | A | B | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6gla | B | A | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6gla | B | B | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | Show | |
| JAK3 | JakA | TK | 6glb | A | A | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | Show | |
| JAK3 | JakA | TK | 6glb | A | B | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | Show | |
| JAK3 | JakA | TK | 6glb | B | A | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | Show | |
| JAK3 | JakA | TK | 6glb | B | B | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | A | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | A | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | B | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | B | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | C | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | C | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | D | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6hzv | D | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | Show | |
| JAK3 | JakA | TK | 6ny4 | A | 4-{[(2r,3r)-1,3-dihydroxybutan-2-yl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 7apf | A | A | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 7apf | A | B | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 7apf | B | A | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 7apf | B | B | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | A | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | A | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | B | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | B | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | C | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | C | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | D | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7apg | D | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 7c3n | A | A | 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile | Human | Show | |
| JAK3 | JakA | TK | 7c3n | A | B | 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile | Human | Show | |
| JAK3 | JakA | TK | 7c3n | A | C | 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile | Human | Show | |
| JAK3 | JakA | TK | 7q6h | A | A | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | Show | |
| JAK3 | JakA | TK | 7q6h | A | B | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | Show | |
| JAK3 | JakA | TK | 7q6h | A | C | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | Show | |
| JAK3 | JakA | TK | 7uyv | A | A | 6-{[(2m)-2-(2-chloro-6-fluorophenyl)-5-oxo-5h-pyrrolo[3,4-b]pyridin-4-yl]amino}-n-ethylpyridine-3-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 7uyv | A | B | 6-{[(2m)-2-(2-chloro-6-fluorophenyl)-5-oxo-5h-pyrrolo[3,4-b]pyridin-4-yl]amino}-n-ethylpyridine-3-carboxamide | Human | Show | |
| KDR | VEGFR | TK | 1vr2 | A | - | Human | Show | | |
| KDR | VEGFR | TK | 1y6a | A | A | n-[5-(ethylsulfonyl)-2-methoxyphenyl]-5-[3-(2-pyridinyl)phenyl]-1,3-oxazol-2-amine | Human | Show | |
