PDB-code
Browse kinase entries (page 176 of 282)
First 172 173 174 PreviousLast180 179 178 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | MAPK1 (Erk2) | MAPK | CMGC | 4zzm | A | 7-ethylsulfonyl-n-(oxan-4-yl)-6,8-dihydro-5h-pyrido[3,4-d]pyrimidin-2-amine | Human | Show |  | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzn | A | A | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzn | A | B | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzo | A | A | n-[2-[[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]amino]phenyl]propanamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzo | A | B | n-[2-[[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]amino]phenyl]propanamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5ax3 | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bue | A | 1-benzyl-4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1h)-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bui | A | 3-(4-fluorophenyl)-5-(pyridin-2-yl)-4,5,6,7-tetrahydro-2h-pyrazolo[4,3-c]pyridine | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5buj | A | A | 4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1h)-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5buj | A | B | 4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1h)-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvd | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-7-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvd | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-7-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bve | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bve | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvf | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-(2-{[(1s,3r)-3-hydroxycyclopentyl]amino}pyrimidin-4-yl)-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvf | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-(2-{[(1s,3r)-3-hydroxycyclopentyl]amino}pyrimidin-4-yl)-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5k4i | A | 1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lcj | A | A | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[5-chloranyl-4-[[2-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lcj | A | B | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[5-chloranyl-4-[[2-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lck | A | A | ~{n}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lck | A | B | ~{n}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5ngu | A | 2-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhf | A | 2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-5-(phenylmethyl)-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhh | A | 5-(2-methoxyethyl)-2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhj | A | 5-(2-methoxyethyl)-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhl | A | (6~{r})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nho | A | (6~{s})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhp | A | 5-(2-methoxyethyl)-1-methyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydropyrrolo[3,2-c]pyridin-4-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhv | A | 7-[2-(oxan-4-ylamino)pyrimidin-4-yl]-3,4-dihydro-2~{h}-pyrrolo[1,2-a]pyrazin-1-one | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v60 | A | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v60 | A | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v61 | A | A | - | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v61 | A | B | - | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v62 | A | A | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridazin-3-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v62 | A | B | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridazin-3-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5wp1 | A | A | 5,7-dihydroxy-4h-1-benzopyran-4-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 5wp1 | A | B | 5,7-dihydroxy-4h-1-benzopyran-4-one | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6d5y | A | - | Human | Show | | |
| MAPK1 (Erk2) | MAPK | CMGC | 6dmg | A | A | - | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6dmg | A | B | ethyl n-{2-chloro-4-[5-(5-{[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]carbamoyl}-1h-pyrrol-3-yl)-1h-pyrazol-4-yl]benzyl}glycinate | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6dmg | A | C | ethyl n-{2-chloro-4-[5-(5-{[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]carbamoyl}-1h-pyrrol-3-yl)-1h-pyrazol-4-yl]benzyl}glycinate | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g54 | A | A | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g54 | A | B | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g8x | A | A | 4-chloranyl-1~{h}-indazol-3-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g8x | A | B | 4-chloranyl-1~{h}-indazol-3-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g91 | A | A | 5-chloranyl-~{n}-(oxan-4-yl)pyrimidin-2-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g91 | A | B | 5-chloranyl-~{n}-(oxan-4-yl)pyrimidin-2-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g92 | A | A | ~{n}-(1,5-dimethylpyrazol-4-yl)-5-methyl-pyrimidin-2-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g92 | A | B | ~{n}-(1,5-dimethylpyrazol-4-yl)-5-methyl-pyrimidin-2-amine | Human | Show | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g93 | A | A | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2,3-dihydroisoindol-1-one | Human | Show | |
