PDB-code
Browse kinase entries (page 205 of 282)
First 201 202 203 PreviousLast209 208 207 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | MET | Met | TK | 5eyd | A | A | 6-[(1~{r})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one | Human | Show |  |
| MET | Met | TK | 5eyd | A | B | 6-[(1~{r})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one | Human | Show | |
| MET | Met | TK | 5hlw | A | 1-[2-(1-ethylpiperidin-4-yl)ethyl]-3-(6-{[6-(thiophen-2-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)urea | Human | Show | | |
| MET | Met | TK | 5hni | X | methyl (6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1h-benzimidazol-2-yl)carbamate | Human | Show | | |
| MET | Met | TK | 5hni | Y | methyl (6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1h-benzimidazol-2-yl)carbamate | Human | Show | | |
| MET | Met | TK | 5ho6 | A | 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea | Human | Show | | |
| MET | Met | TK | 5hoa | A | 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea | Human | Show | | |
| MET | Met | TK | 5hor | A | 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea | Human | Show | | |
| MET | Met | TK | 5hti | A | A | n-[3-fluoro-4-({7-[2-(morpholin-4-yl)ethoxy]-1,6-naphthyridin-4-yl}oxy)phenyl]-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 5hti | A | B | n-[3-fluoro-4-({7-[2-(morpholin-4-yl)ethoxy]-1,6-naphthyridin-4-yl}oxy)phenyl]-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 5t3q | A | n-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | Show | | |
| MET | Met | TK | 5uab | A | A | n-{6-[([1,2,4]triazolo[4,3-a]pyridin-3-yl)sulfanyl]imidazo[1,2-b]pyridazin-2-yl}cyclopropanecarboxamide | Human | Show | |
| MET | Met | TK | 5uab | A | B | n-{6-[([1,2,4]triazolo[4,3-a]pyridin-3-yl)sulfanyl]imidazo[1,2-b]pyridazin-2-yl}cyclopropanecarboxamide | Human | Show | |
| MET | Met | TK | 5uad | A | n-(6-{[6-(1-methyl-1h-pyrazol-4-yl)-1h-benzotriazol-1-yl]methyl}imidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide | Human | Show | | |
| MET | Met | TK | 5ya5 | A | A | 2-[3-(4-methoxybenzyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1h-indole | Human | Show | |
| MET | Met | TK | 5ya5 | A | B | 2-[3-(4-methoxybenzyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1h-indole | Human | Show | |
| MET | Met | TK | 6sd9 | A | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | | |
| MET | Met | TK | 6sdc | A | A | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 6sdc | A | B | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 6sdd | A | n-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | Show | | |
| MET | Met | TK | 6sde | A | volitinib | Human | Show | | |
| MET | Met | TK | 6ubw | A | n-(6-{difluoro[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}imidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide | Human | Show | | |
| MET | Met | TK | 7b3q | A | A | 1-(phenylmethyl)-5~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | Show | |
| MET | Met | TK | 7b3q | A | B | 1-(phenylmethyl)-5~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | Show | |
| MET | Met | TK | 7b3t | A | A | 3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | |
| MET | Met | TK | 7b3t | A | B | 3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | |
| MET | Met | TK | 7b3v | A | A | 3-(3-methyl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | Show | |
| MET | Met | TK | 7b3v | A | B | 3-(3-methyl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | Show | |
| MET | Met | TK | 7b3w | A | A | 3-(6-fluoranyl-1~{h}-indazol-4-yl)-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | Show | |
| MET | Met | TK | 7b3w | A | B | 3-(6-fluoranyl-1~{h}-indazol-4-yl)-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | Show | |
| MET | Met | TK | 7b3z | A | A | 3-[3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | Show | |
| MET | Met | TK | 7b3z | A | B | 3-[3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | Show | |
| MET | Met | TK | 7b40 | A | 3-(phenylmethyl)-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | | |
| MET | Met | TK | 7b41 | A | A | 3-[(2-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | |
| MET | Met | TK | 7b41 | A | B | 3-[(2-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | |
| MET | Met | TK | 7b42 | A | 3-[(3-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | | |
| MET | Met | TK | 7b43 | A | 3-[(4-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | | |
| MET | Met | TK | 7b43 | B | 3-[(4-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | Show | | |
| MET | Met | TK | 7b44 | A | A | 5-methoxy-1~{h}-indazole | Human | Show | |
| MET | Met | TK | 7b44 | A | B | 5-methoxy-1~{h}-indazole | Human | Show | |
| MET | Met | TK | 7v3r | A | A | ~{n}1'-[3-fluoranyl-4-(2-phenylazanylpyrimidin-4-yl)oxy-phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 7v3r | A | B | ~{n}1'-[3-fluoranyl-4-(2-phenylazanylpyrimidin-4-yl)oxy-phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 7v3s | A | A | ~{n}1'-[3-fluoranyl-4-(10~{h}-pyrido[3,2-b][1,4]benzoxazin-4-yloxy)phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 7v3s | A | B | ~{n}1'-[3-fluoranyl-4-(10~{h}-pyrido[3,2-b][1,4]benzoxazin-4-yloxy)phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | Show | |
| MET | Met | TK | 7y4t | A | 2-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-(3-nitrophenyl)pyridazin-3-one | Human | Show | | |
| MET | Met | TK | 7y4u | A | ~{n}-methyl-4-[1-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-oxidanylidene-pyridazin-3-yl]-2-(trifluoromethyl)benzamide | Human | Show | | |
| MET | Met | TK | 8an8 | A | 3-[bis(fluoranyl)methyl]-~{n}-methyl-~{n}-[(1~{r})-8-methyl-5-(3-methyl-1~{h}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide | Human | Show | | |
| MET | Met | TK | 8ans | A | 3-[bis(fluoranyl)methyl]-~{n}-methyl-~{n}-[(1~{r})-8-methyl-5-(3-methyl-1~{h}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide | Human | Show | | |
| MET | Met | TK | 8au3 | A | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | Show | | |
| MET | Met | TK | 8au5 | A | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | Show | |
