PDB-code
Browse kinase entries (page 210 of 282)
First 206 207 208 PreviousLast214 213 212 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | NTRK1 (TRKA) | Trk | TK | 4pmp | A | B | 1-cyclopropyl-1-[3-(1,3-thiazol-2-yl)benzyl]-3-[4-(trifluoromethoxy)phenyl]urea | Human | Show |  |
| NTRK1 (TRKA) | Trk | TK | 4pms | A | A | 4-(naphthalen-1-yl)-1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1h-pyrrolo[3,2-c]pyridine-2-carboxylic acid | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 4pms | A | B | 4-(naphthalen-1-yl)-1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1h-pyrrolo[3,2-c]pyridine-2-carboxylic acid | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 4pmt | A | A | n~4~-[4-(morpholin-4-yl)phenyl]-n~6~-(pyridin-3-ylmethyl)pyrido[3,2-d]pyrimidine-4,6-diamine | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 4pmt | A | B | n~4~-[4-(morpholin-4-yl)phenyl]-n~6~-(pyridin-3-ylmethyl)pyrido[3,2-d]pyrimidine-4,6-diamine | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 4yne | A | A | 6-[(2r)-2-(3-fluorophenyl)pyrrolidin-1-yl]-3-(pyridin-2-yl)imidazo[1,2-b]pyridazine | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 4yne | A | B | 6-[(2r)-2-(3-fluorophenyl)pyrrolidin-1-yl]-3-(pyridin-2-yl)imidazo[1,2-b]pyridazine | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 4yps | A | 4-{6-[(3r)-3-(3-fluorophenyl)morpholin-4-yl]imidazo[1,2-b]pyridazin-3-yl}benzonitrile | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5h3q | A | A | 1-[(3s,4r)-4-[3,4-bis(fluoranyl)phenyl]-1-(2-methoxyethyl)pyrrolidin-3-yl]-3-(5-ethoxy-4-methyl-2-phenyl-pyrazol-3-yl)urea | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5h3q | A | B | 1-[(3s,4r)-4-[3,4-bis(fluoranyl)phenyl]-1-(2-methoxyethyl)pyrrolidin-3-yl]-3-(5-ethoxy-4-methyl-2-phenyl-pyrazol-3-yl)urea | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5i8a | A | A | (6r)-3-(methylsulfanyl)-6-phenyl-1-(1h-pyrazol-3-yl)-6,7-dihydrothieno[3,4-c]pyridin-4(5h)-one | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5i8a | A | B | (6r)-3-(methylsulfanyl)-6-phenyl-1-(1h-pyrazol-3-yl)-6,7-dihydrothieno[3,4-c]pyridin-4(5h)-one | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5jfs | A | A | n-{4-[4-amino-7-(propan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-2-yl}-n'-(2,4-difluorophenyl)urea | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5jfs | A | B | n-{4-[4-amino-7-(propan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-2-yl}-n'-(2,4-difluorophenyl)urea | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5jfv | A | A | n-{5-[4-amino-7-(propan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}-2-(4-chlorophenyl)acetamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5jfv | A | B | n-{5-[4-amino-7-(propan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}-2-(4-chlorophenyl)acetamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5jfw | A | A | 2-(4-cyanophenyl)-n-{5-[7-(propan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}acetamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5jfw | A | B | 2-(4-cyanophenyl)-n-{5-[7-(propan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}acetamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5jfx | A | n-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}-2-(5-chloropyridin-2-yl)acetamide | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5kmi | A | 1-(9~{h}-fluoren-9-yl)-3-(2-methyl-4-phenyl-pyrimidin-5-yl)urea | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5kmj | A | A | ~{n}-(pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)ethanamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5kmj | A | B | ~{n}-(pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)ethanamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5kmk | A | 2-fluoranyl-~{n}-[2-(4-fluorophenyl)-6-methyl-pyridin-3-yl]-4-(trifluoromethyl)benzamide | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5kml | A | 1-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5kmm | A | 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-naphthalen-1-yl-urea | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5kmn | A | 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5kmo | A | 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-pyridin-2-yl-urea | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 5kvt | A | A | entrectinib | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5kvt | A | B | entrectinib | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 5wr7 | A | n-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 6d1y | A | A | 2,4-dichloro-n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6d1y | A | B | 2,4-dichloro-n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6d1z | A | A | 5-{[5-(6-aminopyridin-2-yl)-2-chlorobenzene-1-carbonyl]amino}-1-phenyl-1h-pyrazole-3-carboxamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6d1z | A | B | 5-{[5-(6-aminopyridin-2-yl)-2-chlorobenzene-1-carbonyl]amino}-1-phenyl-1h-pyrazole-3-carboxamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6d20 | A | 5-{[2,4-dichloro-5-(pyridin-2-yl)benzene-1-carbonyl]amino}-n-(2-hydroxy-2-methylpropyl)-1-phenyl-1h-pyrazole-3-carboxamide | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 6d22 | A | - | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 6dkb | A | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 6dkg | A | A | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-4-(2-hydroxy-2-methylpropoxy)benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6dkg | A | B | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-4-(2-hydroxy-2-methylpropoxy)benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6dki | A | A | 6-amino-5-{[(3s)-4,4-difluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}pyrrolidin-3-yl]oxy}-n-methylpyridine-3-carboxamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6dki | A | B | 6-amino-5-{[(3s)-4,4-difluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}pyrrolidin-3-yl]oxy}-n-methylpyridine-3-carboxamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6dkw | A | A | 5-(1-methyl-1h-imidazol-4-yl)-2-[(1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl)oxy]benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6dkw | A | B | 5-(1-methyl-1h-imidazol-4-yl)-2-[(1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl)oxy]benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6dkw | B | A | 5-(1-methyl-1h-imidazol-4-yl)-2-[(1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl)oxy]benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6dkw | B | B | 5-(1-methyl-1h-imidazol-4-yl)-2-[(1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl)oxy]benzamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6iqn | A | 4-[[4-azanyl-3-(4-cyclohexylpiperazin-1-yl)-9,10-bis(oxidanylidene)anthracen-1-yl]amino]benzoic acid | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 6iqn | B | 4-[[4-azanyl-3-(4-cyclohexylpiperazin-1-yl)-9,10-bis(oxidanylidene)anthracen-1-yl]amino]benzoic acid | Human | Show | | |
| NTRK1 (TRKA) | Trk | TK | 6j5l | A | A | n-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1h-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6j5l | A | B | n-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1h-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide | Human | Show | |
| NTRK1 (TRKA) | Trk | TK | 6j5l | A | C | n-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1h-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide | Human | Show | |
