PDB-code
Browse kinase entries (page 220 of 282)
First 216 217 218 PreviousLast224 223 222 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | PIK3C3 | PIK | Atypical | 4oys | A | (8s)-9-[(5-chloranylpyridin-3-yl)methyl]-2-[(3r)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-6,7,8,9a-tetrahydro-3h-pyrimido[1,2-a]pyrimidin-4-one | Human | Show |  | |
| PIK3C3 | PIK | Atypical | 4ph4 | B | A | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4ph4 | B | B | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4uwf | A | - | Human | Show | | |
| PIK3C3 | PIK | Atypical | 4uwg | A | A | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4uwg | A | B | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4uwh | A | A | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4uwh | A | B | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4uwk | A | A | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4uwk | A | B | - | Human | Show | |
| PIK3C3 | PIK | Atypical | 4uwl | A | - | Human | Show | | |
| PIK3C3 | PIK | Atypical | 5anl | A | (8s)-2-(morpholin-4-yl)-9-[2-(propan-2-yloxy)ethyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4h-pyrimido[1,2-a]pyrimidin-4-one | Human | Show | | |
| PIK3C3 | PIK | Atypical | 5enn | A | A | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | |
| PIK3C3 | PIK | Atypical | 5enn | A | B | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | |
| PIK3C3 | PIK | Atypical | 5enn | B | A | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | |
| PIK3C3 | PIK | Atypical | 5enn | B | B | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | |
| PIK3C3 | PIK | Atypical | 6i3u | A | 2-morpholin-4-yl-6-[7-[(2~{r})-1-morpholin-4-ylpropan-2-yl]oxy-9~{h}-thioxanthen-4-yl]pyran-4-one | Human | Show | | |
| PIK3C3 | PIK | Atypical | 6ykg | A | 4-morpholin-4-yl-6-[(2~{r})-2-(phenylmethyl)pyrrolidin-1-yl]-1~{h}-pyridin-2-one | Human | Show | | |
| PIK3C3 | PIK | Atypical | 7bl1 | B | - | Human | Show | | |
| PIK3C3 | PIK | Atypical | 7rsj | A | A | n-{4-[(7r,8r)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide | Human | Show | |
| PIK3C3 | PIK | Atypical | 7rsj | A | B | n-{4-[(7r,8r)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide | Human | Show | |
| PIK3C3 | PIK | Atypical | 7rsp | A | A | (7r,8r)-2-[(3r)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one | Human | Show | |
| PIK3C3 | PIK | Atypical | 7rsp | A | B | (7r,8r)-2-[(3r)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one | Human | Show | |
| PIK3C3 | PIK | Atypical | 7rsv | A | A | (5as,8ar,9s)-2-[(3r)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4h-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one | Human | Show | |
| PIK3C3 | PIK | Atypical | 7rsv | A | B | (5as,8ar,9s)-2-[(3r)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4h-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one | Human | Show | |
| PIK3C3 | PIK | Atypical | 8sor | A | - | Human | Show | | |
| Pik3ca (p110a) | PIK | Atypical | 4a55 | A | pik-108 | Mouse | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 2rd0 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 3hhm | A | (1s,6br,9as,11r,11br)-9a,11b-dimethyl-1-[(methyloxy)methyl]-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3h-furo[4,3,2-de]indeno[4,5-h][2]benzopyran-11-yl acetate | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 3hiz | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 3zim | A | 1-[4-[[2-(1h-indazol-4-yl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-6-methyl-hept-5-ene-1,4-dione | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 4jps | A | A | (2s)-n~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4jps | A | B | (2s)-n~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4l1b | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 4l23 | A | 3-(4-morpholin-4-ylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 4l2y | A | 3-amino-5-[4-(morpholin-4-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 4ovu | A | A | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4ovu | A | B | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4ovv | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 4tuu | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 4tv3 | A | 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 4waf | A | A | n,n-dimethyl-4-[(6r)-6-methyl-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl]benzenesulfonamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4waf | A | B | n,n-dimethyl-4-[(6r)-6-methyl-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl]benzenesulfonamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4ykn | A | A | 3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4ykn | A | B | 3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4zop | A | A | (2s,3r)-n~1~-(8-tert-butyl-4,5-dihydro[1,3]thiazolo[4,5-h]quinazolin-2-yl)-3-methylpyrrolidine-1,2-dicarboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 4zop | A | B | (2s,3r)-n~1~-(8-tert-butyl-4,5-dihydro[1,3]thiazolo[4,5-h]quinazolin-2-yl)-3-methylpyrrolidine-1,2-dicarboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 5dxh | A | methyl {2-[4-(2-chlorophenyl)-4h-1,2,4-triazol-3-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepin-8-yl}carbamate | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5dxh | D | methyl {2-[4-(2-chlorophenyl)-4h-1,2,4-triazol-3-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepin-8-yl}carbamate | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5dxt | A | (2s)-2-({2-[1-(propan-2-yl)-1h-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}oxy)propanamide | Human | Show | |
