PDB-code
Browse kinase entries (page 23 of 282)
First 19 20 21 PreviousLast27 26 25 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | BRAF | RAF | TKL | 4h58 | C | A | - | Human | Show |  |
| BRAF | RAF | TKL | 4h58 | C | B | - | Human | Show | |
| BRAF | RAF | TKL | 4jvg | A | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | Show | | |
| BRAF | RAF | TKL | 4jvg | B | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | Show | | |
| BRAF | RAF | TKL | 4jvg | C | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | Show | | |
| BRAF | RAF | TKL | 4jvg | D | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | Show | | |
| BRAF | RAF | TKL | 4ksp | A | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | Show | | |
| BRAF | RAF | TKL | 4ksp | B | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | Show | | |
| BRAF | RAF | TKL | 4ksq | A | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | Show | | |
| BRAF | RAF | TKL | 4ksq | B | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | Show | | |
| BRAF | RAF | TKL | 4mbj | A | 2,6-difluoro-n-(1h-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide | Human | Show | | |
| BRAF | RAF | TKL | 4mbj | B | 2,6-difluoro-n-(1h-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide | Human | Show | | |
| BRAF | RAF | TKL | 4mne | B | A | - | Human | Show | |
| BRAF | RAF | TKL | 4mne | B | B | - | Human | Show | |
| BRAF | RAF | TKL | 4mne | C | A | - | Human | Show | |
| BRAF | RAF | TKL | 4mne | C | B | - | Human | Show | |
| BRAF | RAF | TKL | 4mne | F | A | - | Human | Show | |
| BRAF | RAF | TKL | 4mne | F | B | - | Human | Show | |
| BRAF | RAF | TKL | 4mne | G | A | - | Human | Show | |
| BRAF | RAF | TKL | 4mne | G | B | - | Human | Show | |
| BRAF | RAF | TKL | 4mnf | A | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | Show | |
| BRAF | RAF | TKL | 4mnf | A | B | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | Show | |
| BRAF | RAF | TKL | 4mnf | B | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | Show | |
| BRAF | RAF | TKL | 4mnf | B | B | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | Show | |
| BRAF | RAF | TKL | 4pp7 | A | n-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 4pp7 | B | n-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 4r5y | A | 5-({(1r,1as,6br)-1-[5-(trifluoromethyl)-1h-benzimidazol-2-yl]-1a,6b-dihydro-1h-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1h)-one | Human | Show | | |
| BRAF | RAF | TKL | 4r5y | B | 5-({(1r,1as,6br)-1-[5-(trifluoromethyl)-1h-benzimidazol-2-yl]-1a,6b-dihydro-1h-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1h)-one | Human | Show | | |
| BRAF | RAF | TKL | 4rzv | A | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 4rzv | B | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 4rzw | A | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | Show | | |
| BRAF | RAF | TKL | 4rzw | B | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | Show | | |
| BRAF | RAF | TKL | 4wo5 | A | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 4wo5 | B | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 4xv1 | A | n'-(3-{[5-(2-cyclopropylpyrimidin-5-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)-n-ethyl-n-methylsulfuric diamide | Human | Show | | |
| BRAF | RAF | TKL | 4xv1 | B | - | Human | Show | | |
| BRAF | RAF | TKL | 4xv2 | A | dabrafenib | Human | Show | | |
| BRAF | RAF | TKL | 4xv2 | B | dabrafenib | Human | Show | | |
| BRAF | RAF | TKL | 4xv3 | A | n'-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-n-ethyl-n-methylsulfuric diamide | Human | Show | | |
| BRAF | RAF | TKL | 4xv3 | B | - | Human | Show | | |
| BRAF | RAF | TKL | 4xv9 | A | A | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-4-(trifluoromethyl)benzenesulfonamide | Human | Show | |
| BRAF | RAF | TKL | 4xv9 | A | B | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-4-(trifluoromethyl)benzenesulfonamide | Human | Show | |
| BRAF | RAF | TKL | 4yht | A | 3-[(5-chloro-7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-n-methyl-4-(morpholin-4-yl)benzenesulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 4yht | B | 3-[(5-chloro-7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-n-methyl-4-(morpholin-4-yl)benzenesulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 5c9c | A | A | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | Show | |
| BRAF | RAF | TKL | 5c9c | A | B | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | Show | |
| BRAF | RAF | TKL | 5c9c | B | A | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | Show | |
| BRAF | RAF | TKL | 5c9c | B | B | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | Show | |
| BRAF | RAF | TKL | 5csw | A | dabrafenib | Human | Show | | |
| BRAF | RAF | TKL | 5csw | B | dabrafenib | Human | Show | |
