PDB-code
Browse kinase entries (page 221 of 282)
First 217 218 219 PreviousLast225 224 223 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | PIK3CA (p110a) | PIK | Atypical | 5fi4 | A | A | ~{n}-[6-[5-azanyl-6-[(2~{s})-1,1,1-tris(fluoranyl)propan-2-yl]oxy-pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]ethanamide | Human | Show |  |
| PIK3CA (p110a) | PIK | Atypical | 5fi4 | A | B | ~{n}-[6-[5-azanyl-6-[(2~{s})-1,1,1-tris(fluoranyl)propan-2-yl]oxy-pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]ethanamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 5itd | A | 5-{4-[3-(4-acetylpiperazine-1-carbonyl)phenyl]quinazolin-6-yl}-2-methoxypyridine-3-carbonitrile | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sw8 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5swg | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5swo | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5swp | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5swr | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5swt | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sx8 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sx9 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxa | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxb | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxc | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxd | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxe | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxf | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxi | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxj | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5sxk | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5ubr | A | 1-[4-(3-{4-amino-5-[1-(oxan-4-yl)-1h-pyrazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-7-yl}phenyl)piperazin-1-yl]ethan-1-one | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5uk8 | A | A | (r)-4-(6-(1-(cyclopropylsulfonyl)cyclopropyl)-2-(1h-indol-4-yl)pyrimidin-4-yl)-3-methylmorpholine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 5uk8 | A | B | (r)-4-(6-(1-(cyclopropylsulfonyl)cyclopropyl)-2-(1h-indol-4-yl)pyrimidin-4-yl)-3-methylmorpholine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 5ukj | A | n,n-dimethyl-4-[(6r)-6-methyl-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl]benzenesulfonamide | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5ul1 | A | A | 3-amino-6-(4-{[(2s)-1-(dimethylamino)propan-2-yl]sulfonyl}phenyl)-n-phenylpyrazine-2-carboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 5ul1 | A | B | 3-amino-6-(4-{[(2s)-1-(dimethylamino)propan-2-yl]sulfonyl}phenyl)-n-phenylpyrazine-2-carboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 5xgh | A | 3-[(4-fluorophenyl)methylamino]-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5xgi | A | 3-azanyl-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 5xgj | A | 3-(4-morpholin-4-ylfuro[3,2-d]pyrimidin-2-yl)-5-[(phenylmethyl)amino]phenol | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 6gvf | A | A | 5-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 6gvf | A | B | 5-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 6gvg | A | 5-(6-azanyl-4-methyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 6gvh | A | A | 5-(6-azanyl-4-chloranyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 6gvh | A | B | 5-(6-azanyl-4-chloranyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 6gvi | A | A | 3-(2-azanyl-1,3-benzoxazol-5-yl)-1-propan-2-yl-pyrazolo[3,4-d]pyrimidine-4,6-diamine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 6gvi | A | B | 3-(2-azanyl-1,3-benzoxazol-5-yl)-1-propan-2-yl-pyrazolo[3,4-d]pyrimidine-4,6-diamine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 6nct | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 6oac | A | 4-(difluoromethyl)-5-{4-[(3s)-3-methylmorpholin-4-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}pyridin-2-amine | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 6pys | A | A | (3s)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2h-indol-2-one | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 6pys | A | B | (3s)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2h-indol-2-one | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7jiu | A | A | (3s)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9h-purin-6-yl]-3-methyl-1,3-dihydro-2h-indol-2-one | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7jiu | A | B | (3s)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9h-purin-6-yl]-3-methyl-1,3-dihydro-2h-indol-2-one | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7k6m | A | A | 2,2-difluoroethyl (3s)-3-{[2'-amino-5-fluoro-2-(morpholin-4-yl)[4,5'-bipyrimidin]-6-yl]amino}-3-(hydroxymethyl)pyrrolidine-1-carboxylate | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7k6m | A | B | 2,2-difluoroethyl (3s)-3-{[2'-amino-5-fluoro-2-(morpholin-4-yl)[4,5'-bipyrimidin]-6-yl]amino}-3-(hydroxymethyl)pyrrolidine-1-carboxylate | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7k6n | A | A | tert-butyl (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-3-methylpyrrolidine-1-carboxylate | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7k6n | A | B | tert-butyl (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-3-methylpyrrolidine-1-carboxylate | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7k6o | A | A | (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-n-methylpyrrolidine-1-sulfonamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7k6o | A | B | (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-n-methylpyrrolidine-1-sulfonamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7k71 | A | 2-(morpholin-4-yl)[4,5'-bipyrimidin]-2'-amine | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 7mlk | A | A | 4-[6-(3,4,5-trimethoxyanilino)pyrazin-2-yl]benzamide | Human | Show | |
