PDB-code
Browse kinase entries (page 25 of 282)
First 21 22 23 PreviousLast29 28 27 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
![]() | BRAF | RAF | TKL | 6n0q | B | A | n-[4-methyl-3-(1-methyl-2-oxo-2,3-dihydro-1h-benzimidazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6n0q | B | B | n-[4-methyl-3-(1-methyl-2-oxo-2,3-dihydro-1h-benzimidazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6nsq | A | 5-[(4-amino-1-ethyl-1h-pyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-n-(4-chlorophenyl)-6-methylisoquinolin-1-amine | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6nsq | B | 5-[(4-amino-1-ethyl-1h-pyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-n-(4-chlorophenyl)-6-methylisoquinolin-1-amine | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6nyb | A | phosphothiophosphoric acid-adenylate ester | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6p3d | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6p7g | A | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6p7g | B | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6p7g | C | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6p7g | D | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6pp9 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6pp9 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0j | A | A | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0j | A | B | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0j | B | A | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0j | B | B | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0k | A | - | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6q0k | B | - | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6q0t | A | A | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0t | A | B | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0t | B | A | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6q0t | B | B | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6u2g | B | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6u2h | C | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6u2h | D | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6uan | B | - | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6uan | C | - | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6uuo | A | 1-[4-{[1-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)-3-(pyrimidin-5-yl)-1h-pyrrolo[3,2-b]pyridin-5-yl](methyl)amino}pyridin-1(4h)-yl]ethan-1-one | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6uuo | B | 1-[4-{[1-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)-3-(pyrimidin-5-yl)-1h-pyrrolo[3,2-b]pyridin-5-yl](methyl)amino}pyridin-1(4h)-yl]ethan-1-one | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6v2u | A | dabrafenib | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6v2u | B | dabrafenib | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6v2w | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6v2w | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6v34 | A | 6-amino-5-chloro-n-[(1r)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6v34 | B | 6-amino-5-chloro-n-[(1r)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 6xag | C | A | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6xag | D | A | - | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6xfp | A | A | 4-amino-n-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6xfp | A | B | 4-amino-n-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 6xlo | A | 3-(2-cyanopropan-2-yl)-n-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 7k0v | A | A | n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 7k0v | A | B | n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 7m0t | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 7m0u | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 7m0v | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 7m0v | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 7m0w | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | BRAF | RAF | TKL | 7m0x | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 7m0x | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | BRAF | RAF | TKL | 7m0y | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |


