PDB-code
Browse kinase entries (page 264 of 282)
First 260 261 262 PreviousLast268 267 266 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | SYK | Syk | TK | 6zcu | A | A | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show |  |
| SYK | Syk | TK | 6zcu | A | B | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show | |
| SYK | Syk | TK | 6zcx | A | A | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-piperidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | Show | |
| SYK | Syk | TK | 6zcx | A | B | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-piperidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | Show | |
| SYK | Syk | TK | 6zcy | A | A | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-pyrrolidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | Show | |
| SYK | Syk | TK | 6zcy | A | B | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-pyrrolidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | Show | |
| SYK | Syk | TK | 8bi2 | A | 10,13,23-trimethyl-16-oxa-2,4,8,9,13,19,23,30-octazapentacyclo[19.5.2.1^{3,7}.1^{8,11}.0^{24,28}]triaconta-1(27),3,5,7(30),9,11(29),21,24(28),25-nonaen-20-one | Human | Show | | |
| SYK | Syk | TK | 8x5k | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | Show | |
| SYK | Syk | TK | 8x5k | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | Show | |
| TAOK3 (TAO3) | STE20 | STE | 6bdn | A | A | adenosine-5'-diphosphate | Human | Show | |
| TAOK3 (TAO3) | STE20 | STE | 6bdn | A | B | adenosine-5'-diphosphate | Human | Show | |
| Tbk1 (TBK1) | IKK | Other | 4jl9 | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | Show | | |
| Tbk1 (TBK1) | IKK | Other | 4jlc | A | 3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acid | Mouse | Show | | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | Show | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | Show | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | Show | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | Show | |
| TBK1 | IKK | Other | 4eut | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4eut | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4eut | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4eut | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4euu | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4euu | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4euu | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4euu | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4im0 | A | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | Show | |
| TBK1 | IKK | Other | 4im0 | A | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | Show | |
| TBK1 | IKK | Other | 4im2 | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4im2 | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4im3 | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4im3 | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | |
| TBK1 | IKK | Other | 4iw0 | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | | |
| TBK1 | IKK | Other | 4iwo | A | n-{3-[(5-cyclopropyl-2-{[3-(2-oxopyrrolidin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | Show | | |
| TBK1 | IKK | Other | 4iwp | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | | |
| TBK1 | IKK | Other | 4iwq | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | Show | | |
| TBK1 | IKK | Other | 5w5v | A | 2-amino-7-(1-methylethyl)-5-oxo-5h-chromeno[2,3-b]pyridine-3-carboxylic acid | Human | Show | | |
| TBK1 | IKK | Other | 6bny | A | 2-amino-7-(propan-2-yl)-3-(1h-tetrazol-5-yl)-5h-[1]benzopyrano[2,3-b]pyridin-5-one | Human | Show | | |
| TBK1 | IKK | Other | 6bod | A | ethyl 2-amino-5-oxo-7-(propan-2-yl)-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylate | Human | Show | | |
| TBK1 | IKK | Other | 6boe | A | 2-amino-5-oxo-7-(propan-2-yl)-n-(1h-tetrazol-5-yl)-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxamide | Human | Show | | |
| TBK1 | IKK | Other | 6cq0 | A | 2-amino-7-[3-(dimethylamino)propyl]-5-oxo-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid | Human | Show | | |
| TBK1 | IKK | Other | 6cq4 | A | 2-amino-7-(4,4-difluorocyclohexyl)-5-oxo-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid | Human | Show | | |
| TBK1 | IKK | Other | 6cq5 | A | 2-amino-7-(1,1-dioxo-1lambda~6~-thian-4-yl)-5-oxo-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid | Human | Show | | |
| TBK1 | IKK | Other | 6nt9 | A | - | Human | Show | | |
| TBK1 | IKK | Other | 6nt9 | B | - | Human | Show | | |
| TBK1 | IKK | Other | 6o8b | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | | |
| TBK1 | IKK | Other | 6o8b | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | Show | | |
| TBK1 | IKK | Other | 6rsr | A | ~{n}-(cyclopropen-1-ylmethyl)-2-[[4-[[4-[3,3,3-tris(fluoranyl)propanoyl]piperazin-1-yl]methyl]pyridin-2-yl]amino]-1~{h}-benzimidazole-5-carboxamide | Human | Show | | |
| TBK1 | IKK | Other | 6rst | A | 1-[4-[(1~{r})-1-[2-[[5-[1-(cyclopropylmethyl)pyrazol-4-yl]-1~{h}-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-tris(fluoranyl)propan-1-one | Human | Show | | |
| TBK1 | IKK | Other | 6rsu | A | 3,3,3-tris(fluoranyl)-1-[4-[(1~{r})-1-[2-[[(2~{s})-5-(5-propan-2-yloxypyrimidin-4-yl)-2,3-dihydro-1~{h}-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]propan-1-one | Human | Show | | |
| TEK (TIE2) | Tie | TK | 1fvr | A | - | Human | Show | |
