PDB-code
Browse kinase entries (page 271 of 282)
First 267 268 269 PreviousLast275 274 273 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | TTK | TTK | Other | 5ei6 | A | ~{n}-(2,4-dimethoxyphenyl)-5-(1-methylpyrazol-4-yl)isoquinolin-3-amine | Human | Show |  | |
| TTK | TTK | Other | 5ei8 | A | ~{n}-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Human | Show | | |
| TTK | TTK | Other | 5ljj | A | n~6~-cyclohexyl-n~2~-(4-morpholin-4-ylphenyl)-9h-purine-2,6-diamine | Human | Show | | |
| TTK | TTK | Other | 5mrb | A | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | Show | | |
| TTK | TTK | Other | 5n7v | A | ~{n}6-cyclohexyl-~{n}2-(2-methyl-4-morpholin-4-yl-phenyl)-7~{h}-purine-2,6-diamine | Human | Show | | |
| TTK | TTK | Other | 5n84 | A | ~{n}-cyclopropyl-4-[8-(2-methylpropylamino)imidazo[1,2-a]pyrazin-3-yl]benzamide | Human | Show | | |
| TTK | TTK | Other | 5n87 | A | ~{n}-(2,6-diethylphenyl)-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | Show | | |
| TTK | TTK | Other | 5n93 | A | 4-[[4-azanyl-6-(~{tert}-butylamino)-5-cyano-pyridin-2-yl]amino]benzamide | Human | Show | | |
| TTK | TTK | Other | 5n9s | A | (2~{r})-2-(4-fluorophenyl)-~{n}-[4-[2-[(2-methoxy-4-methylsulfonyl-phenyl)amino]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide | Human | Show | | |
| TTK | TTK | Other | 5na0 | A | ~{n}-[3,5-diethyl-1-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]pyrazol-4-yl]-2-[[2-methoxy-4-[4-(2-methoxyethanoyl)piperazin-1-yl]phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | Show | | |
| TTK | TTK | Other | 5nad | A | bay 1217389 | Human | Show | | |
| TTK | TTK | Other | 5ntt | A | A | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | Show | |
| TTK | TTK | Other | 5ntt | A | B | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | Show | |
| TTK | TTK | Other | 5o91 | A | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | Show | | |
| TTK | TTK | Other | 6b4w | A | 4-{[4-(cyclopentyloxy)-5-(2-methyl-1,3-benzoxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl]amino}-3-methoxy-n-methylbenzamide | Human | Show | | |
| TTK | TTK | Other | 6gvj | A | - | Human | Show | | |
| TTK | TTK | Other | 6h3k | A | ~{n}8-(2,2-dimethylpropyl)-~{n}2-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methyl-pyrido[3,4-d]pyrimidine-2,8-diamine | Human | Show | | |
| TTK | TTK | Other | 6n6o | A | 4-({5-chloro-4-[(cis-4-hydroxy-4-methylcyclohexyl)oxy]-7h-pyrrolo[2,3-d]pyrimidin-2-yl}amino)-n,n-dimethyl-3-{[(2r)-1,1,1-trifluoropropan-2-yl]oxy}benzamide | Human | Show | | |
| TTK | TTK | Other | 6tn9 | A | A | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | Show | |
| TTK | TTK | Other | 6tn9 | A | B | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | Show | |
| TTK | TTK | Other | 6tnb | A | (2~{r})-2-(4-fluorophenyl)-~{n}-[4-[2-[(2-methoxy-4-methylsulfonyl-phenyl)amino]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide | Human | Show | | |
| TTK | TTK | Other | 6tnc | A | n-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide | Human | Show | | |
| TTK | TTK | Other | 6tnd | A | A | bay 1217389 | Human | Show | |
| TTK | TTK | Other | 6tnd | A | B | bay 1217389 | Human | Show | |
| TTK | TTK | Other | 7chm | A | 4-(cyclohexylamino)-2-[(2-methoxy-4-morpholin-4-ylcarbonyl-phenyl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | Show | | |
| TTK | TTK | Other | 7chn | A | 4-(cyclohexylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | Show | | |
| TTK | TTK | Other | 7cht | A | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(oxan-4-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | Show | | |
| TTK | TTK | Other | 7cil | A | A | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | Show | |
| TTK | TTK | Other | 7cil | A | B | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | Show | |
| TTK | TTK | Other | 7cja | A | 4-(cyclopentylmethylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | Show | | |
| TTK | TTK | Other | 7clh | A | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(methylamino)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | Show | | |
| TTK | TTK | Other | 7lqd | A | ~{n}-(2,6-diethylphenyl)-2-[[4-(4-methylpiperazin-1-yl)-2-(propanoylamino)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | Show | | |
| TTN | MLCK | CAMK | 1tki | A | - | Human | Show | | |
| TTN | MLCK | CAMK | 1tki | B | - | Human | Show | | |
| TTN | MLCK | CAMK | 4jnw | A | A | - | Human | Show | |
| TTN | MLCK | CAMK | 4jnw | A | B | - | Human | Show | |
| TTN | MLCK | CAMK | 4jnw | B | A | - | Human | Show | |
| TTN | MLCK | CAMK | 4jnw | B | B | - | Human | Show | |
| TTN | MLCK | CAMK | 6ygn | A | - | Human | Show | | |
| TTN | MLCK | CAMK | 6ygn | B | - | Human | Show | | |
| Tyk2 (TYK2) | JakA | TK | 4e1z | A | n-[5-(4-{[(3-chlorophenyl)sulfonyl]amino}phenyl)-1h-indazol-3-yl]furan-2-carboxamide | Mouse | Show | | |
| Tyk2 (TYK2) | JakA | TK | 4e20 | A | n-[4-(3-amino-1h-indazol-5-yl)phenyl]-3-chlorobenzenesulfonamide | Mouse | Show | | |
| TYK2 | JakA | TK | 3lxn | A | 3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | Human | Show | | |
| TYK2 | JakA | TK | 3lxp | A | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | | |
| TYK2 | JakA | TK | 3nyx | A | A | n-{5-[(7-chloroquinolin-4-yl)sulfanyl]-1,3,4-thiadiazol-2-yl}thiophene-2-carboxamide | Human | Show | |
| TYK2 | JakA | TK | 3nyx | A | B | n-{5-[(7-chloroquinolin-4-yl)sulfanyl]-1,3,4-thiadiazol-2-yl}thiophene-2-carboxamide | Human | Show | |
| TYK2 | JakA | TK | 3nz0 | A | A | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | |
| TYK2 | JakA | TK | 3nz0 | A | B | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | |
| TYK2 | JakA | TK | 4gfo | A | A | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | Show | |
| TYK2 | JakA | TK | 4gfo | A | B | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | Show | |
