PDB-code
Browse kinase entries (page 57 of 282)
First 53 54 55 PreviousLast61 60 59 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | CDK7 | CDK | CMGC | 1ua2 | C | adenosine-5'-triphosphate | Human | Show |  | |
| CDK7 | CDK | CMGC | 1ua2 | D | adenosine-5'-triphosphate | Human | Show | | |
| CDK7 | CDK | CMGC | 6o9l | 8 | - | Human | Show | | |
| CDK7 | CDK | CMGC | 6xbz | J | phosphothiophosphoric acid-adenylate ester | Human | Show | | |
| CDK7 | CDK | CMGC | 6xd3 | J | n-(3-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-4-{[4-(dimethylamino)butanoyl]amino}benzamide | Human | Show | | |
| CDK7 | CDK | CMGC | 7b5o | J | A | (3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol | Human | Show | |
| CDK7 | CDK | CMGC | 7b5o | J | B | (3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol | Human | Show | |
| CDK7 | CDK | CMGC | 7b5q | J | A | (3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol | Human | Show | |
| CDK7 | CDK | CMGC | 7b5q | J | B | (3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol | Human | Show | |
| CDK7 | CDK | CMGC | 7nvr | 8 | - | Human | Show | | |
| CDK7 | CDK | CMGC | 8bvw | I | - | Human | Show | | |
| CDK7 | CDK | CMGC | 8byq | I | - | Human | Show | | |
| CDK7 | CDK | CMGC | 8p4z | A | A | 2-[(3r)-piperidin-3-yl]oxy-8-propan-2-yl-n-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine | Human | Show | |
| CDK7 | CDK | CMGC | 8p4z | A | B | 2-[(3r)-piperidin-3-yl]oxy-8-propan-2-yl-n-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine | Human | Show | |
| CDK7 | CDK | CMGC | 8pyr | A | A | - | Human | Show | |
| CDK7 | CDK | CMGC | 8pyr | A | B | - | Human | Show | |
| CDK8 | CDK | CMGC | 3rgf | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | Show | |
| CDK8 | CDK | CMGC | 3rgf | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | Show | |
| CDK8 | CDK | CMGC | 4crl | A | cortistatin a | Human | Show | | |
| CDK8 | CDK | CMGC | 4f6s | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | Show | | |
| CDK8 | CDK | CMGC | 4f6u | A | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea | Human | Show | |
| CDK8 | CDK | CMGC | 4f6u | A | B | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea | Human | Show | |
| CDK8 | CDK | CMGC | 4f6w | A | n-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-4-[2-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)ethyl]piperazine-1-carboxamide | Human | Show | | |
| CDK8 | CDK | CMGC | 4f70 | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[2-(morpholin-4-yl)ethyl]urea | Human | Show | | |
| CDK8 | CDK | CMGC | 4f7j | A | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(2-hydroxyethyl)urea | Human | Show | |
| CDK8 | CDK | CMGC | 4f7j | A | B | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(2-hydroxyethyl)urea | Human | Show | |
| CDK8 | CDK | CMGC | 4f7l | A | tert-butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)propyl]carbamate | Human | Show | | |
| CDK8 | CDK | CMGC | 4f7n | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(5-hydroxypentyl)urea | Human | Show | | |
| CDK8 | CDK | CMGC | 4f7s | A | A | n-(2-phenylethyl)quinazolin-4-amine | Human | Show | |
| CDK8 | CDK | CMGC | 4f7s | A | B | n-(2-phenylethyl)quinazolin-4-amine | Human | Show | |
| CDK8 | CDK | CMGC | 4g6l | A | - | Human | Show | | |
| CDK8 | CDK | CMGC | 5bnj | A | 8-{3-chloro-5-[4-(1-methyl-1h-pyrazol-4-yl)phenyl]pyridin-4-yl}-2,8-diazaspiro[4.5]decan-1-one | Human | Show | | |
| CDK8 | CDK | CMGC | 5cei | A | A | 4-(4-iodophenoxy)-n-methylthieno[2,3-c]pyridine-2-carboxamide | Human | Show | |
| CDK8 | CDK | CMGC | 5cei | A | B | 4-(4-iodophenoxy)-n-methylthieno[2,3-c]pyridine-2-carboxamide | Human | Show | |
| CDK8 | CDK | CMGC | 5fgk | A | A | 8-[3-(3-azanyl-2~{h}-indazol-6-yl)-5-chloranyl-pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one | Human | Show | |
| CDK8 | CDK | CMGC | 5fgk | A | B | 8-[3-(3-azanyl-2~{h}-indazol-6-yl)-5-chloranyl-pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one | Human | Show | |
| CDK8 | CDK | CMGC | 5hbe | A | A | 8-[3-chloranyl-5-[1-methyl-2,2-bis(oxidanylidene)-3~{h}-2,1-benzothiazol-5-yl]pyridin-4-yl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one | Human | Show | |
| CDK8 | CDK | CMGC | 5hbe | A | B | 8-[3-chloranyl-5-[1-methyl-2,2-bis(oxidanylidene)-3~{h}-2,1-benzothiazol-5-yl]pyridin-4-yl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one | Human | Show | |
| CDK8 | CDK | CMGC | 5hbh | A | 5-[5-chloranyl-4-[1-(2-methoxyethyl)-1,8-diazaspiro[4.5]decan-8-yl]pyridin-3-yl]-1-methyl-3~{h}-2,1-benzothiazole 2,2-dioxide | Human | Show | | |
| CDK8 | CDK | CMGC | 5hbj | A | A | 8-[2-azanyl-3-chloranyl-5-(1-methylindazol-5-yl)pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one | Human | Show | |
| CDK8 | CDK | CMGC | 5hbj | A | B | 8-[2-azanyl-3-chloranyl-5-(1-methylindazol-5-yl)pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one | Human | Show | |
| CDK8 | CDK | CMGC | 5hnb | A | A | [6-hydroxy-3-(3-methylbenzyl)-1h-indazol-5-yl][(3s)-3-hydroxypyrrolidin-1-yl]methanone | Human | Show | |
| CDK8 | CDK | CMGC | 5hnb | A | B | [6-hydroxy-3-(3-methylbenzyl)-1h-indazol-5-yl][(3s)-3-hydroxypyrrolidin-1-yl]methanone | Human | Show | |
| CDK8 | CDK | CMGC | 5hvy | A | A | n-{(3s)-1-[2-(methylamino)pyrimidin-4-yl]pyrrolidin-3-yl}-n'-{4-[(morpholin-4-yl)methyl]-3-(trifluoromethyl)phenyl}urea | Human | Show | |
| CDK8 | CDK | CMGC | 5hvy | A | B | n-{(3s)-1-[2-(methylamino)pyrimidin-4-yl]pyrrolidin-3-yl}-n'-{4-[(morpholin-4-yl)methyl]-3-(trifluoromethyl)phenyl}urea | Human | Show | |
| CDK8 | CDK | CMGC | 5i5z | A | n-methyl-8-(1-methyl-2,2-dioxo-2,3-dihydro-1h-2lambda~6~,1-benzothiazol-5-yl)-1,6-naphthyridine-2-carboxamide | Human | Show | | |
| CDK8 | CDK | CMGC | 5icp | A | A | [(2s)-2-(4-chlorophenyl)pyrrolidin-1-yl](5-methylimidazo[5,1-b][1,3,4]thiadiazol-2-yl)methanone | Human | Show | |
| CDK8 | CDK | CMGC | 5icp | A | B | [(2s)-2-(4-chlorophenyl)pyrrolidin-1-yl](5-methylimidazo[5,1-b][1,3,4]thiadiazol-2-yl)methanone | Human | Show | |
| CDK8 | CDK | CMGC | 5idn | A | A | [(2s)-2-(4-chlorophenyl)pyrrolidin-1-yl](3-methyl-1h-pyrazolo[3,4-b]pyridin-5-yl)methanone | Human | Show | |
| CDK8 | CDK | CMGC | 5idn | A | B | [(2s)-2-(4-chlorophenyl)pyrrolidin-1-yl](3-methyl-1h-pyrazolo[3,4-b]pyridin-5-yl)methanone | Human | Show | |
