PDB-code
Search results (31 entries covering 19 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | GRK2 (BARK1) | GRK | AGC | 6u7c | A | 5-[(3s,4r)-3-{[(2h-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-n-[(2h-indazol-3-yl)methyl]benzamide | Human | Show |  | |
| GRK2 (BARK1) | GRK | AGC | 5uvc | A | n-benzyl-3-({[5-(pyridin-4-yl)-4h-1,2,4-triazol-3-yl]methyl}amino)benzamide | Human | Show | | |
| GRK2 (BARK1) | GRK | AGC | 5he1 | A | B | (4~{s})-4-[4-fluoranyl-3-(isoquinolin-1-ylmethylcarbamoyl)phenyl]-~{n}-(1~{h}-indazol-5-yl)-6-methyl-2-oxidanylidene-3,4-dihydro-1~{h}-pyrimidine-5-carboxamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5ukk | A | B | 5-[(3s,4r)-3-{[(2h-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-n-[(pyridin-2-yl)methyl]benzamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 7pwd | A | A | 4-chloranyl-n-[2-(4-chlorophenyl)ethyl]thieno[2,3-c]pyridine-2-carboxamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 7pwd | A | B | 4-chloranyl-n-[2-(4-chlorophenyl)ethyl]thieno[2,3-c]pyridine-2-carboxamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 7k7l | A | A | 3-benzyl-6-(1h-pyrazol-4-yl)quinazolin-4(3h)-one | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5uuu | A | B | 3-({[4-methyl-5-(pyridin-4-yl)-4h-1,2,4-triazol-3-yl]methyl}amino)-n-[2-(trifluoromethyl)benzyl]benzamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 4pnk | A | B | (4s)-4-(4-fluorophenyl)-n-(2h-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5wg5 | A | A | 5-{[(3s,4r)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-2h-indazole | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5wg3 | A | 2-fluoro-5-[(3s,4r)-3-{[(1h-indazol-5-yl)oxy]methyl}piperidin-4-yl]-n-[(1h-pyrazol-3-yl)methyl]benzamide | Human | Show | | |
| GRK2 (BARK1) | GRK | AGC | 3krw | A | balanol | Human | Show | | |
| GRK2 (BARK1) | GRK | AGC | 4mk0 | A | B | 5-{[(3s,4r)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-1h-isoindol-1-one | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 4pnk | A | A | (4s)-4-(4-fluorophenyl)-n-(2h-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 6c2y | A | (4r,5r,6s)-4-[4-fluoro-3-({[3-(methoxymethyl)-1,2,4-oxadiazol-5-yl]methyl}carbamoyl)phenyl]-n-(2h-indazol-5-yl)-6-methyl-2-oxohexahydropyrimidine-5-carboxamide | Human | Show | | |
| GRK2 (BARK1) | GRK | AGC | 5wg5 | A | B | 5-{[(3s,4r)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-2h-indazole | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5wg4 | A | B | 2-fluoro-5-[(3s,4r)-3-{[(1h-indazol-5-yl)oxy]methyl}piperidin-4-yl]-n-[(pyridin-2-yl)methyl]benzamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 3v5w | A | A | paroxetine | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 7k7l | A | B | 3-benzyl-6-(1h-pyrazol-4-yl)quinazolin-4(3h)-one | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 7k7z | A | A | 3-benzyl-7-(1h-pyrazol-4-yl)quinazolin-4(3h)-one | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5ukk | A | A | 5-[(3s,4r)-3-{[(2h-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-n-[(pyridin-2-yl)methyl]benzamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5ukl | A | A | 2-{5-[(3s,4r)-3-{[(2h-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluorophenyl}-n-[2-(1h-pyrazol-4-yl)ethyl]acetamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 3v5w | A | B | paroxetine | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 4mk0 | A | A | 5-{[(3s,4r)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-1h-isoindol-1-one | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5uuu | A | A | 3-({[4-methyl-5-(pyridin-4-yl)-4h-1,2,4-triazol-3-yl]methyl}amino)-n-[2-(trifluoromethyl)benzyl]benzamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 3krx | A | balanol | Human | Show | | |
| GRK2 (BARK1) | GRK | AGC | 3cik | A | - | Human | Show | | |
| GRK2 (BARK1) | GRK | AGC | 5he1 | A | A | (4~{s})-4-[4-fluoranyl-3-(isoquinolin-1-ylmethylcarbamoyl)phenyl]-~{n}-(1~{h}-indazol-5-yl)-6-methyl-2-oxidanylidene-3,4-dihydro-1~{h}-pyrimidine-5-carboxamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5wg4 | A | A | 2-fluoro-5-[(3s,4r)-3-{[(1h-indazol-5-yl)oxy]methyl}piperidin-4-yl]-n-[(pyridin-2-yl)methyl]benzamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 5ukl | A | B | 2-{5-[(3s,4r)-3-{[(2h-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluorophenyl}-n-[2-(1h-pyrazol-4-yl)ethyl]acetamide | Human | Show | |
| GRK2 (BARK1) | GRK | AGC | 7k7z | A | B | 3-benzyl-7-(1h-pyrazol-4-yl)quinazolin-4(3h)-one | Human | Show | |
