Search results (193 entries covering 22 PDB structures)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
VRK1VRKCK18v42AA-HumanShow
VRK1VRKCK18v42AB-HumanShow
VRK1VRKCK16cnxAB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16dd4AB-HumanShow
VRK1VRKCK13op5AA[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK15uvfA(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12lavA9-HumanShow
VRK1VRKCK12lavA7-HumanShow
VRK1VRKCK12lavA16-HumanShow
VRK1VRKCK16dd4DA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-dipropyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16bruDB(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12lavA5-HumanShow
VRK1VRKCK16cnxCA(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12ktyA13-HumanShow
VRK1VRKCK12lavA12-HumanShow
VRK1VRKCK16bp0DB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16bruCB-HumanShow
VRK1VRKCK12ktyA14-HumanShow
VRK1VRKCK16bu6DA4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol)HumanShow
VRK1VRKCK16npnB(7r)-7-methyl-2-[(3-oxo-2,3-dihydro-1h-indazol-6-yl)amino]-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK13op5CA[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK16cnxDA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK15ukfC4-{[(z)-(7-oxo-6,7-dihydro-8h-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}benzene-1-sulfonamideHumanShow
VRK1VRKCK12kulA2-HumanShow
VRK1VRKCK16cqhDA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-ethyl-7-methyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK15ukfD4-{[(z)-(7-oxo-6,7-dihydro-8h-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}benzene-1-sulfonamideHumanShow
VRK1VRKCK16vzhD(7~{r})-2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7-dimethyl-8-prop-2-ynyl-7~{h}-pteridin-6-oneHumanShow
VRK1VRKCK16dd4DB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-dipropyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cswCA-HumanShow
VRK1VRKCK12kulA17-HumanShow
VRK1VRKCK12lavA18-HumanShow
VRK1VRKCK12ktyA5-HumanShow
VRK1VRKCK12rsvA12-HumanShow
VRK1VRKCK16bu6CB-HumanShow
VRK1VRKCK16bruAA-HumanShow
VRK1VRKCK16bu6DB4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol)HumanShow
VRK1VRKCK12lavA1-HumanShow
VRK1VRKCK13op5DB[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK16cswCB-HumanShow
VRK1VRKCK12ktyA18-HumanShow
VRK1VRKCK12rsvA5-HumanShow
VRK1VRKCK16dd4CA-HumanShow
VRK1VRKCK16cfmBB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16bp0BA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12ktyA4-HumanShow
VRK1VRKCK16cfmDA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12lavA14-HumanShow
VRK1VRKCK16ac9CAphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK12lavA19-HumanShow
VRK1VRKCK16cqhDB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-ethyl-7-methyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12kulA12-HumanShow
VRK1VRKCK16vxuB(7r)-8-(cyclopropylmethyl)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cfmAA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12lavA6-HumanShow
VRK1VRKCK15uvfD(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cnxBA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cnxCB(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cmmBB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16ac9CBphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK12rsvA3-HumanShow
VRK1VRKCK12kulA14-HumanShow
VRK1VRKCK16dd4BB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-dipropyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cmmAB-HumanShow
VRK1VRKCK16btwCB-HumanShow
VRK1VRKCK12lavA15-HumanShow
VRK1VRKCK16ac9ABphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK16bp0DA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12ktyA3-HumanShow
VRK1VRKCK16btwCA-HumanShow
VRK1VRKCK16cmmCA-HumanShow
VRK1VRKCK13op5CB[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK16vzhB(7~{r})-2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7-dimethyl-8-prop-2-ynyl-7~{h}-pteridin-6-oneHumanShow
VRK1VRKCK16bp0BB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12ktyA8-HumanShow
VRK1VRKCK16npnA(7r)-7-methyl-2-[(3-oxo-2,3-dihydro-1h-indazol-6-yl)amino]-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12lavA17-HumanShow
VRK1VRKCK12lavA10-HumanShow
VRK1VRKCK16bu6BB4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol)HumanShow
VRK1VRKCK12rsvA7-HumanShow
VRK1VRKCK16bu6CA-HumanShow
VRK1VRKCK12rsvA17-HumanShow
VRK1VRKCK16bu6AB4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol)HumanShow
VRK1VRKCK16cmmAA-HumanShow
VRK1VRKCK16cqhAB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-ethyl-7-methyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16bruCA-HumanShow
VRK1VRKCK12rsvA2-HumanShow
VRK1VRKCK12ktyA15-HumanShow
VRK1VRKCK12ktyA12-HumanShow
VRK1VRKCK16bu6AA4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol)HumanShow
VRK1VRKCK15uvfB(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16ac9BAphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK16cnxBB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12kulA5-HumanShow
VRK1VRKCK12rsvA14-HumanShow
VRK1VRKCK12rsvA18-HumanShow
VRK1VRKCK16cswBA(7r)-5-butyl-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK13op5BA[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK12lavA2-HumanShow
VRK1VRKCK12rsvA6-HumanShow
VRK1VRKCK16npnC(7r)-7-methyl-2-[(3-oxo-2,3-dihydro-1h-indazol-6-yl)amino]-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12ktyA10-HumanShow
VRK1VRKCK16cswAA-HumanShow
VRK1VRKCK16bruAB-HumanShow
VRK1VRKCK16cfmAB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16dd4CB-HumanShow
VRK1VRKCK12ktyA20-HumanShow
VRK1VRKCK16cqhAA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-ethyl-7-methyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16vzhA-HumanShow
VRK1VRKCK16btwBA2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cmmCB-HumanShow
VRK1VRKCK16ac9AAphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK16vzhC-HumanShow
VRK1VRKCK16bu6BA4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol)HumanShow
VRK1VRKCK12rsvA1-HumanShow
VRK1VRKCK15ukfA4-{[(z)-(7-oxo-6,7-dihydro-8h-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}benzene-1-sulfonamideHumanShow
VRK1VRKCK16dd4BA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-dipropyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12lavA11-HumanShow
VRK1VRKCK15uvfC(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cfmCB-HumanShow
VRK1VRKCK16btwDB2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK13op5AB[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK12rsvA13-HumanShow
VRK1VRKCK12kulA6-HumanShow
VRK1VRKCK16bruBA(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12ktyA17-HumanShow
VRK1VRKCK12lavA4-HumanShow
VRK1VRKCK16cnxDB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK13op5BB[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK16npnD(7r)-7-methyl-2-[(3-oxo-2,3-dihydro-1h-indazol-6-yl)amino]-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cqhCB-HumanShow
VRK1VRKCK12kulA13-HumanShow
VRK1VRKCK12ktyA9-HumanShow
VRK1VRKCK12ktyA7-HumanShow
VRK1VRKCK12lavA20-HumanShow
VRK1VRKCK12rsvA16-HumanShow
VRK1VRKCK12kulA8-HumanShow
VRK1VRKCK16ac9BBphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK16btwAA2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12kulA19-HumanShow
VRK1VRKCK16btwBB2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cmmDB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12lavA13-HumanShow
VRK1VRKCK12ktyA1-HumanShow
VRK1VRKCK16bp0CB-HumanShow
VRK1VRKCK16cfmDB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16bp0AA-HumanShow
VRK1VRKCK16cmmDA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cswBB(7r)-5-butyl-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cqhCA-HumanShow
VRK1VRKCK12kulA9-HumanShow
VRK1VRKCK12kulA10-HumanShow
VRK1VRKCK16dd4AA-HumanShow
VRK1VRKCK16btwAB2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK15ukfB4-{[(z)-(7-oxo-6,7-dihydro-8h-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}benzene-1-sulfonamideHumanShow
VRK1VRKCK16cswDB(7r)-5-butyl-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12kulA7-HumanShow
VRK1VRKCK12kulA3-HumanShow
VRK1VRKCK12kulA11-HumanShow
VRK1VRKCK16cqhBB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-ethyl-7-methyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cqhBA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-ethyl-7-methyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12kulA18-HumanShow
VRK1VRKCK16bruDA(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16bp0CA-HumanShow
VRK1VRKCK12ktyA11-HumanShow
VRK1VRKCK16cfmCA-HumanShow
VRK1VRKCK16cswDA(7r)-5-butyl-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cmmBA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK13op5DA[4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrileHumanShow
VRK1VRKCK12kulA20-HumanShow
VRK1VRKCK12ktyA16-HumanShow
VRK1VRKCK16cnxAA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK16cfmBA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12rsvA10-HumanShow
VRK1VRKCK16bp0AB-HumanShow
VRK1VRKCK12rsvA9-HumanShow
VRK1VRKCK12kulA15-HumanShow
VRK1VRKCK12kulA16-HumanShow
VRK1VRKCK16ac9DAphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK12rsvA11-HumanShow
VRK1VRKCK12kulA1-HumanShow
VRK1VRKCK12ktyA6-HumanShow
VRK1VRKCK12rsvA4-HumanShow
VRK1VRKCK16btwDA2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12rsvA15-HumanShow
VRK1VRKCK16ac9DBphosphoaminophosphonic acid-adenylate esterHumanShow
VRK1VRKCK16bruBB(7s)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5h)-oneHumanShow
VRK1VRKCK12ktyA2-HumanShow
VRK1VRKCK12ktyA19-HumanShow
VRK1VRKCK12kulA4-HumanShow
VRK1VRKCK16cswAB-HumanShow
VRK1VRKCK12rsvA8-HumanShow
VRK1VRKCK12lavA3-HumanShow
VRK1VRKCK12lavA8-HumanShow