PDB-code
Search results (32 entries covering 14 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | TNK2 (ACK) | Ack | TK | 8fe9 | A | n-[(1s)-1-benzyl-2-[(6-chloro-2-oxo-1h-quinolin-4-yl)methylamino]-2-oxo-ethyl]-4-hydroxy-2-oxo-1h-quinoline-6-carbo | Human | Show |  | |
| TNK2 (ACK) | Ack | TK | 6vqm | A | 2-({4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl}amino)-9-methyl-5,7-dihydro-6h-pyrimido[5,4-d][1,3]benzodiazepin-6-one | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 6vqm | B | 2-({4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl}amino)-9-methyl-5,7-dihydro-6h-pyrimido[5,4-d][1,3]benzodiazepin-6-one | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 5zxb | A | A | n-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | Show | |
| TNK2 (ACK) | Ack | TK | 4id7 | A | cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 3eqr | B | n~3~-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-n~6~-(4-piperazin-1-ylphenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,6-diamine | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4hzr | B | A | - | Human | Show | |
| TNK2 (ACK) | Ack | TK | 4hzr | A | B | - | Human | Show | |
| TNK2 (ACK) | Ack | TK | 4hzs | A | - | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 5zxb | A | B | n-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | Show | |
| TNK2 (ACK) | Ack | TK | 1u4d | B | debromohymenialdisine | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 7kp6 | A | B | 5-chloro-n~2~-[4-(4-methylpiperazin-1-yl)phenyl]-n~4~-{[(2r)-oxolan-2-yl]methyl}pyrimidine-2,4-diamine | Human | Show | |
| TNK2 (ACK) | Ack | TK | 3eqp | B | n-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 1u46 | A | - | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 5zxb | B | A | n-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | Show | |
| TNK2 (ACK) | Ack | TK | 1u54 | A | phosphomethylphosphonic acid adenylate ester | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4hzs | B | - | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4ewh | A | 6-{4-[2-(dimethylamino)ethoxy]phenyl}-n-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4ewh | B | 6-{4-[2-(dimethylamino)ethoxy]phenyl}-n-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 3eqp | A | n-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4hzs | C | - | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4hzs | D | - | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4hzr | B | B | - | Human | Show | |
| TNK2 (ACK) | Ack | TK | 7kp6 | A | A | 5-chloro-n~2~-[4-(4-methylpiperazin-1-yl)phenyl]-n~4~-{[(2r)-oxolan-2-yl]methyl}pyrimidine-2,4-diamine | Human | Show | |
| TNK2 (ACK) | Ack | TK | 1u4d | A | debromohymenialdisine | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 8hmt | A | B | 6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2s)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one | Human | Show | |
| TNK2 (ACK) | Ack | TK | 8hmt | A | A | 6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2s)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one | Human | Show | |
| TNK2 (ACK) | Ack | TK | 3eqr | A | n~3~-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-n~6~-(4-piperazin-1-ylphenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,6-diamine | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 1u54 | B | phosphomethylphosphonic acid adenylate ester | Human | Show | | |
| TNK2 (ACK) | Ack | TK | 4hzr | A | A | - | Human | Show | |
| TNK2 (ACK) | Ack | TK | 5zxb | B | B | n-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | Show | |
| TNK2 (ACK) | Ack | TK | 1u46 | B | - | Human | Show | |
