PDB-code
Search results (41 entries covering 19 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | EPHB4 (EphB4) | Eph | TK | 6fnj | B | A | 4-methyl-3-[(2-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | Show |  |
| EPHB4 (EphB4) | Eph | TK | 2vwy | A | A | n'-(5-chloro-1,3-benzodioxol-4-yl)-n-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2yn8 | B | staurosporine | Human | Show | | |
| EPHB4 (EphB4) | Eph | TK | 2vwy | A | B | n'-(5-chloro-1,3-benzodioxol-4-yl)-n-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fni | A | B | 4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnj | B | B | 4-methyl-3-[(2-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnk | A | A | 1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vwz | A | A | n-[3-[[4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl]amino]phenyl]methanesulfonamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2xvd | A | A | {4-methyl-3-[(1-methylethyl)(2-{[3-(methylsulfonyl)-5-morpholin-4-ylphenyl]amino}pyrimidin-4-yl)amino]phenyl}methanol | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2x9f | A | A | n^4^-1h-indazol-4-yl-n^2^-[3-(methylsulfonyl)phenyl]pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vwv | A | B | n'-(3-chloro-4-methoxy-phenyl)-n-(3,4,5-trimethoxyphenyl)-1,3,5-triazine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnl | A | A | - | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2yn8 | A | staurosporine | Human | Show | | |
| EPHB4 (EphB4) | Eph | TK | 2vwv | A | A | n'-(3-chloro-4-methoxy-phenyl)-n-(3,4,5-trimethoxyphenyl)-1,3,5-triazine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 3zew | B | B | staurosporine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vx1 | A | A | 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fni | A | A | 4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 4aw5 | A | B | (3z)-5-[(1-ethylpiperidin-4-yl)amino]-3-[(5-methoxy-1h-benzimidazol-2-yl)(phenyl)methylidene]-1,3-dihydro-2h-indol-2-one | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnj | A | A | 4-methyl-3-[(2-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnj | A | B | 4-methyl-3-[(2-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 4bb4 | A | A | n-(2-methoxyethyl)-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vx0 | A | A | n'-(5-chloro-1,3-benzodioxol-4-yl)-n-(3-morpholin-4-ylphenyl)pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vww | A | B | n'-(5-chloro-1,3-benzodioxol-4-yl)-n-(3,4,5- trimethoxyphenyl)pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vwx | A | A | 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnm | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vwz | A | B | n-[3-[[4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl]amino]phenyl]methanesulfonamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnm | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2xvd | A | B | {4-methyl-3-[(1-methylethyl)(2-{[3-(methylsulfonyl)-5-morpholin-4-ylphenyl]amino}pyrimidin-4-yl)amino]phenyl}methanol | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vx1 | A | B | 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 4aw5 | A | A | (3z)-5-[(1-ethylpiperidin-4-yl)amino]-3-[(5-methoxy-1h-benzimidazol-2-yl)(phenyl)methylidene]-1,3-dihydro-2h-indol-2-one | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 3zew | B | A | staurosporine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vx0 | A | B | n'-(5-chloro-1,3-benzodioxol-4-yl)-n-(3-morpholin-4-ylphenyl)pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 3zew | A | A | staurosporine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnl | A | B | - | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 6fnk | A | B | 1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 4bb4 | A | B | n-(2-methoxyethyl)-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vwx | A | B | 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 3zew | A | B | staurosporine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vww | A | A | n'-(5-chloro-1,3-benzodioxol-4-yl)-n-(3,4,5- trimethoxyphenyl)pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2x9f | A | B | n^4^-1h-indazol-4-yl-n^2^-[3-(methylsulfonyl)phenyl]pyrimidine-2,4-diamine | Human | Show | |
| EPHB4 (EphB4) | Eph | TK | 2vwu | A | n-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine | Human | Show | |
