PDB-code
Browse kinase entries (page 108 of 282)
First 104 105 106 PreviousLast112 111 110 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | EGFR | EGFR | TK | 7jxi | A | B | n-[(3r,4r)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-methyl-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show |  |
| EGFR | EGFR | TK | 7jxk | A | A | n-[(3r,4r)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-methyl-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7jxk | A | B | n-[(3r,4r)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-methyl-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7jxl | A | A | n-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide | Human | Show | |
| EGFR | EGFR | TK | 7jxl | A | B | n-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide | Human | Show | |
| EGFR | EGFR | TK | 7jxm | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| EGFR | EGFR | TK | 7jxp | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 7jxp | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 7jxq | A | A | (2r)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2h-isoindol-2-yl}-n-(1,3-thiazol-2-yl)acetamide | Human | Show | |
| EGFR | EGFR | TK | 7jxq | A | B | (2r)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2h-isoindol-2-yl}-n-(1,3-thiazol-2-yl)acetamide | Human | Show | |
| EGFR | EGFR | TK | 7jxw | A | A | n-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1h-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide | Human | Show | |
| EGFR | EGFR | TK | 7jxw | A | B | n-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1h-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide | Human | Show | |
| EGFR | EGFR | TK | 7k1h | A | (2r)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2h-isoindol-2-yl}-n-(1,3-thiazol-2-yl)acetamide | Human | Show | | |
| EGFR | EGFR | TK | 7k1i | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 7k1i | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 7kxz | A | (20r)-10,15,20-trimethyl-2-[(4-methylpiperazin-1-yl)methyl]-18,19,20,21-tetrahydro-15h,17h-12,8-(metheno)pyrazolo[3',4':2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-7(6h)-one | Human | Show | | |
| EGFR | EGFR | TK | 7ky0 | A | (20r)-10,15,20-trimethyl-2-[(4-methylpiperazin-1-yl)methyl]-18,19,20,21-tetrahydro-15h,17h-12,8-(metheno)pyrazolo[3',4':2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-7(6h)-one | Human | Show | | |
| EGFR | EGFR | TK | 7lg8 | A | 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3r)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazine-2-carboxamide | Human | Show | | |
| EGFR | EGFR | TK | 7lgs | A | A | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7lgs | A | B | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7lgs | B | A | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7lgs | B | B | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7lgs | C | A | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7lgs | C | B | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7lgs | D | A | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7lgs | D | B | ~{n}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 7ltx | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| EGFR | EGFR | TK | 7oxb | A | 2-[2-(3-methoxyphenyl)pyrimidin-4-yl]-1'-prop-2-enoyl-spiro[5,6-dihydro-1~{h}-pyrrolo[3,2-c]pyridine-7,4'-piperidine]-4-one | Human | Show | | |
| EGFR | EGFR | TK | 7si1 | A | A | - | Human | Show | |
| EGFR | EGFR | TK | 7si1 | A | B | - | Human | Show | |
| EGFR | EGFR | TK | 7si1 | A | C | - | Human | Show | |
| EGFR | EGFR | TK | 7syd | A | B | - | Human | Show | |
| EGFR | EGFR | TK | 7sye | A | - | Human | Show | | |
| EGFR | EGFR | TK | 7sz0 | A | B | - | Human | Show | |
| EGFR | EGFR | TK | 7sz1 | A | - | Human | Show | | |
| EGFR | EGFR | TK | 7sz5 | A | - | Human | Show | | |
| EGFR | EGFR | TK | 7sz7 | A | - | Human | Show | | |
| EGFR | EGFR | TK | 7t4i | A | propan-2-yl 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-5-(propanoylamino)phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate | Human | Show | | |
| EGFR | EGFR | TK | 7t4j | A | propan-2-yl 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-5-(propanoylamino)phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate | Human | Show | | |
| EGFR | EGFR | TK | 7tvd | A | - | Human | Show | | |
| EGFR | EGFR | TK | 7u98 | A | 19-chloro-18-fluoro-22-methoxy-8,9,11,12,14,15-hexahydro-21h-4,6-ethenopyrimido[5,4-m][1,4,7,10,15]benzotetraoxazacycloheptadecine | Human | Show | | |
| EGFR | EGFR | TK | 7u99 | A | 19-chloro-22-methoxy-8,9,11,12,14,15-hexahydro-21h-4,6-ethenopyrimido[5,4-m][1,4,7,10,15]benzotetraoxazacycloheptadecine | Human | Show | | |
| EGFR | EGFR | TK | 7u9a | A | 4-(5-chloro-4-fluoro-2-hydroxyanilino)-7-methoxyquinazolin-6-ol | Human | Show | | |
| EGFR | EGFR | TK | 7ukv | A | n-[5-{[(4p)-4-{4-[(dimethylamino)methyl]-3-phenyl-1h-pyrazol-1-yl}pyrimidin-2-yl]amino}-4-methoxy-2-(morpholin-4-yl)phenyl]propanamide | Human | Show | | |
| EGFR | EGFR | TK | 7ukw | A | A | - | Human | Show | |
| EGFR | EGFR | TK | 7ukw | A | B | - | Human | Show | |
| EGFR | EGFR | TK | 7vra | A | A | 25-chloro-11-(ethylsulfonyl)-44-morpholino-11h-5,12-dioxa-3-aza-1(3,6)-indola-2(4,2)-pyrimidina-4(1,3)-benzenacyclododecaphane | Human | Show | |
| EGFR | EGFR | TK | 7vra | A | B | 25-chloro-11-(ethylsulfonyl)-44-morpholino-11h-5,12-dioxa-3-aza-1(3,6)-indola-2(4,2)-pyrimidina-4(1,3)-benzenacyclododecaphane | Human | Show | |
| EGFR | EGFR | TK | 7vre | A | 5-chloranyl-n-[5-chloranyl-2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-(1-ethylsulfonylindol-3-yl)pyrimidin-2-amine | Human | Show | | |
| EGFR | EGFR | TK | 7zym | A | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | Show | |
