PDB-code
Search results (35 entries covering 18 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
![]() | PIK3C3 | PIK | Atypical | 4oys | A | (8s)-9-[(5-chloranylpyridin-3-yl)methyl]-2-[(3r)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-6,7,8,9a-tetrahydro-3h-pyrimido[1,2-a]pyrimidin-4-one | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 7rsj | A | B | n-{4-[(7r,8r)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 3ls8 | A | A | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 6i3u | A | 2-morpholin-4-yl-6-[7-[(2~{r})-1-morpholin-4-ylpropan-2-yl]oxy-9~{h}-thioxanthen-4-yl]pyran-4-one | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 7rsv | A | A | (5as,8ar,9s)-2-[(3r)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4h-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 3ihy | A | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 3ihy | C | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 5anl | A | (8s)-2-(morpholin-4-yl)-9-[2-(propan-2-yloxy)ethyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4h-pyrimido[1,2-a]pyrimidin-4-one | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 3ls8 | A | B | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 3ihy | D | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 4ph4 | B | B | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 7rsp | A | B | (7r,8r)-2-[(3r)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 7rsp | A | A | (7r,8r)-2-[(3r)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 7rsj | A | A | n-{4-[(7r,8r)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 6ykg | A | 4-morpholin-4-yl-6-[(2~{r})-2-(phenylmethyl)pyrrolidin-1-yl]-1~{h}-pyridin-2-one | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 8sor | A | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 4uwk | A | B | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4uwh | A | A | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4uwg | A | B | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 5enn | B | A | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4uwk | A | A | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4uwg | A | A | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4uwf | A | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 3ls8 | B | B | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 7rsv | A | B | (5as,8ar,9s)-2-[(3r)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4h-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4uwl | A | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 3ls8 | B | A | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4ph4 | B | A | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 5enn | A | A | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 5enn | B | B | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 4uwh | A | B | - | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 5enn | A | B | 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol | Human | Show | ![]() |
![]() | PIK3C3 | PIK | Atypical | 3ihy | B | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 3ihy | E | - | Human | Show | ![]() | |
![]() | PIK3C3 | PIK | Atypical | 7bl1 | B | - | Human | Show | ![]() |


