Search results (59 entries covering 40 PDB structures)

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#	Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	File
	STK24 (MST3)	STE20	STE	4o27	B		adenosine-5'-diphosphate	Human	Show
	STK24 (MST3)	STE20	STE	3ckw	A	A	-	Human	Show
	STK24 (MST3)	STE20	STE	7b33	A		8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[4-[6-[bis(fluoranyl)methyl]pyridin-2-yl]-2-chloranyl-phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	4qmn	A	B	4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile	Human	Show
	STK24 (MST3)	STE20	STE	8bzj	A	A	8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	8bzj	A	B	8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	8bzi	A	B	8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	3a7f	A		-	Human	Show
	STK24 (MST3)	STE20	STE	4qmq	A	A	1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine	Human	Show
	STK24 (MST3)	STE20	STE	4qmv	A		n-{2-[(1s,4r)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide	Human	Show
	STK24 (MST3)	STE20	STE	3a7j	A		adenosine-5'-diphosphate	Human	Show
	STK24 (MST3)	STE20	STE	7b31	A	A	1-[(5-azanyl-1,3-dioxan-2-yl)methyl]-3-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-7-(methylamino)-1,6-naphthyridin-2-one	Human	Show
	STK24 (MST3)	STE20	STE	7b34	A		8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-fluoranyl-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	7b35	B		8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-methoxy-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	4qms	A	B	n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	STK24 (MST3)	STE20	STE	4qms	A	A	n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	STK24 (MST3)	STE20	STE	4qmz	A		n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide	Human	Show
	STK24 (MST3)	STE20	STE	4qmx	A		n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine	Human	Show
	STK24 (MST3)	STE20	STE	3zhp	C		-	Human	Show
	STK24 (MST3)	STE20	STE	3zhp	D		-	Human	Show
	STK24 (MST3)	STE20	STE	4qmt	A		n-[2-oxo-3-((e)-phenyl{[4-(piperidin-1-ylmethyl)phenyl]imino}methyl)-2,6-dihydro-1h-indol-5-yl]ethanesulfonamide	Human	Show
	STK24 (MST3)	STE20	STE	4u8z	A		3-[4-(morpholin-4-yl)-7h-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile	Human	Show
	STK24 (MST3)	STE20	STE	7b30	A		8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	STK24 (MST3)	STE20	STE	4qmw	A	A	1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine	Human	Show
	STK24 (MST3)	STE20	STE	4qml	A		phosphoaminophosphonic acid-adenylate ester	Human	Show
	STK24 (MST3)	STE20	STE	3a7g	A		-	Human	Show
	STK24 (MST3)	STE20	STE	7b32	A		8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[(2-methoxyphenyl)amino]pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	7b31	A	B	1-[(5-azanyl-1,3-dioxan-2-yl)methyl]-3-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-7-(methylamino)-1,6-naphthyridin-2-one	Human	Show
	STK24 (MST3)	STE20	STE	3a7i	A		adenine	Human	Show
	STK24 (MST3)	STE20	STE	3ckx	A		staurosporine	Human	Show
	STK24 (MST3)	STE20	STE	4w8d	A		5-(1-methyl-1h-pyrazol-4-yl)-4-(morpholin-4-yl)-7h-pyrrolo[2,3-d]pyrimidine	Human	Show
	STK24 (MST3)	STE20	STE	4qmy	A		staurosporine	Human	Show
	STK24 (MST3)	STE20	STE	4qmu	A	A	4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide	Human	Show
	STK24 (MST3)	STE20	STE	8qlt	A	B	8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	8qlq	A	A	macrocyclic inhibitor	Human	Show
	STK24 (MST3)	STE20	STE	8qlt	A	A	8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	8qlr	A		8-(4-azanylbutyl)-2-[1,3-bis(oxidanyl)propan-2-ylamino]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	8qls	A	B	8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(3-morpholin-4-ylpropylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	4qmo	A	A	(8z)-8-(1h-imidazol-5-ylmethylidene)-6,8-dihydro-7h-[1,3]thiazolo[5,4-e]indol-7-one	Human	Show
	STK24 (MST3)	STE20	STE	4qna	A		2-(4,6-diamino-1,3,5-triazin-2-yl)phenol	Human	Show
	STK24 (MST3)	STE20	STE	3a7g	B		-	Human	Show
	STK24 (MST3)	STE20	STE	8qlq	A	B	macrocyclic inhibitor	Human	Show
	STK24 (MST3)	STE20	STE	4qo9	A		n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide	Human	Show
	STK24 (MST3)	STE20	STE	4qmq	A	B	1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine	Human	Show
	STK24 (MST3)	STE20	STE	4qmo	A	B	(8z)-8-(1h-imidazol-5-ylmethylidene)-6,8-dihydro-7h-[1,3]thiazolo[5,4-e]indol-7-one	Human	Show
	STK24 (MST3)	STE20	STE	4qo9	B		n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide	Human	Show
	STK24 (MST3)	STE20	STE	3a7h	A		adenosine-5'-triphosphate	Human	Show
	STK24 (MST3)	STE20	STE	4qmu	A	B	4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide	Human	Show
	STK24 (MST3)	STE20	STE	3ckw	A	B	-	Human	Show
	STK24 (MST3)	STE20	STE	4w8e	A		3-{4-[(2r)-2-(5-methyl-1,2,4-oxadiazol-3-yl)morpholin-4-yl]-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile	Human	Show
	STK24 (MST3)	STE20	STE	8qls	A	C	8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(3-morpholin-4-ylpropylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	3a7h	B		adenosine-5'-triphosphate	Human	Show
	STK24 (MST3)	STE20	STE	4qmn	A	A	4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile	Human	Show
	STK24 (MST3)	STE20	STE	8qls	A	A	8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(3-morpholin-4-ylpropylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	8bzi	A	A	8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	4qmw	A	B	1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine	Human	Show
	STK24 (MST3)	STE20	STE	4qmp	A		5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide	Human	Show
	STK24 (MST3)	STE20	STE	7b35	A		8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-methoxy-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one	Human	Show
	STK24 (MST3)	STE20	STE	4qmm	A		1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea	Human	Show

Division of Medicinal Chemistry - Vrije Universiteit Amsterdam