PDB-code
Search results (85 entries covering 24 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | RIPK2 | RIPK | TKL | 8aza | B | - | Human | Show |  | |
| RIPK2 | RIPK | TKL | 6sze | B | B | 5-amino-1-phenylpyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | P | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6sze | A | A | 5-amino-1-phenylpyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 6s1f | D | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 6s1f | B | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 6es0 | A | 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid | Human | Show | | |
| RIPK2 | RIPK | TKL | 6szj | A | A | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | F | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5j7b | A | 6-(tert-butylsulfonyl)-n-(5-fluoro-2h-indazol-3-yl)quinolin-4-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6szj | B | B | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 6rn8 | B | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphate | Human | Show | | |
| RIPK2 | RIPK | TKL | 6ul8 | A | A | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 6ul8 | A | B | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 4c8b | B | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5o | N | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar4 | B | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6es0 | B | 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar8 | B | 2,6-bis(fluoranyl)-n-[3-[5-[2-[(3-methylsulfonylphenyl)amino]pyrimidin-4-yl]-2-morpholin-4-yl-1,3-thiazol-4-yl]phenyl]benzenesulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar7 | A | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | J | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar5 | B | B | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 6hmx | B | 6-~{tert}-butylsulfonyl-~{n}-(3,4-dimethyl-1~{h}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar5 | A | A | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5ng3 | A | - | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar2 | A | A | - | Human | Show | |
| RIPK2 | RIPK | TKL | 6fu5 | A | ~{n}-[5-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-2-methoxy-phenyl]propane-1-sulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar7 | B | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | B | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6s1f | C | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar5 | A | B | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5ng3 | D | - | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5j | B | n-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar3 | B | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 5j79 | B | B | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | Show | |
| RIPK2 | RIPK | TKL | 5ng3 | B | - | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar8 | A | 2,6-bis(fluoranyl)-n-[3-[5-[2-[(3-methylsulfonylphenyl)amino]pyrimidin-4-yl]-2-morpholin-4-yl-1,3-thiazol-4-yl]phenyl]benzenesulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5o | D | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6szj | A | B | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | A | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ng3 | C | - | Human | Show | | |
| RIPK2 | RIPK | TKL | 6rn8 | A | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphate | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5o | C | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ng0 | A | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 6ul8 | B | B | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar5 | B | A | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5j79 | A | B | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | G | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6hmx | A | 6-~{tert}-butylsulfonyl-~{n}-(3,4-dimethyl-1~{h}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5j79 | B | A | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar3 | A | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | K | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5o | M | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ng2 | B | B | staurosporine | Human | Show | |
| RIPK2 | RIPK | TKL | 6fu5 | B | ~{n}-[5-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-2-methoxy-phenyl]propane-1-sulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 4c8b | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ng0 | A | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar4 | A | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar3 | A | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar7 | B | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | O | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6ul8 | B | A | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar3 | B | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar2 | B | A | - | Human | Show | |
| RIPK2 | RIPK | TKL | 5j79 | A | A | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5o | H | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5o | E | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5j7b | B | 6-(tert-butylsulfonyl)-n-(5-fluoro-2h-indazol-3-yl)quinolin-4-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ng2 | A | B | staurosporine | Human | Show | |
| RIPK2 | RIPK | TKL | 5ng2 | B | A | staurosporine | Human | Show | |
| RIPK2 | RIPK | TKL | 6s1f | A | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5o | I | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 5ar2 | A | B | - | Human | Show | |
| RIPK2 | RIPK | TKL | 6szj | B | A | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5ng0 | B | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar2 | B | B | - | Human | Show | |
| RIPK2 | RIPK | TKL | 5ar7 | A | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | Show | |
| RIPK2 | RIPK | TKL | 6sze | A | B | 5-amino-1-phenylpyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 5ng0 | B | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| RIPK2 | RIPK | TKL | 5ng2 | A | A | staurosporine | Human | Show | |
| RIPK2 | RIPK | TKL | 5w5j | A | n-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide | Human | Show | | |
| RIPK2 | RIPK | TKL | 5w5o | L | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | Show | | |
| RIPK2 | RIPK | TKL | 6sze | B | A | 5-amino-1-phenylpyrazole-4-carboxamide | Human | Show | |
| RIPK2 | RIPK | TKL | 6rna | A | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethanol | Human | Show | | |
| RIPK2 | RIPK | TKL | 6rna | B | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethanol | Human | Show | |
