PDB-code
Browse kinase entries (page 11 of 282)
First 7 8 9 PreviousLast15 14 13 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | AKT1 | Akt | AGC | 4gv1 | A | B | 4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide | Human | Show |  |
| AKT1 | Akt | AGC | 5kcv | A | 3-[3-[4-(1-azanylcyclobutyl)phenyl]-5-phenyl-imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine | Human | Show | | |
| AKT1 | Akt | AGC | 6buu | A | A | - | Human | Show | |
| AKT1 | Akt | AGC | 6buu | A | B | - | Human | Show | |
| AKT1 | Akt | AGC | 6buu | A | C | - | Human | Show | |
| AKT1 | Akt | AGC | 6buu | B | A | - | Human | Show | |
| AKT1 | Akt | AGC | 6buu | B | B | - | Human | Show | |
| AKT1 | Akt | AGC | 6buu | B | C | - | Human | Show | |
| AKT1 | Akt | AGC | 6ccy | A | A | (5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-one | Human | Show | |
| AKT1 | Akt | AGC | 6ccy | A | B | (5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-one | Human | Show | |
| AKT1 | Akt | AGC | 6hhf | A | borussertib | Human | Show | | |
| AKT1 | Akt | AGC | 6hhg | A | ~{n}-[2-chloranyl-5-[[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]carbamoylamino]phenyl]propanamide | Human | Show | | |
| AKT1 | Akt | AGC | 6hhh | A | ~{n}-[4-[4-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperazin-1-yl]phenyl]propanamide | Human | Show | | |
| AKT1 | Akt | AGC | 6hhi | A | ~{n}-[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]-3-(propanoylamino)benzamide | Human | Show | | |
| AKT1 | Akt | AGC | 6hhj | A | ~{n}-[1-methyl-2-oxidanylidene-3-[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]benzimidazol-5-yl]propanamide | Human | Show | | |
| AKT1 | Akt | AGC | 6npz | A | A | - | Human | Show | |
| AKT1 | Akt | AGC | 6npz | A | B | - | Human | Show | |
| AKT1 | Akt | AGC | 6npz | B | A | - | Human | Show | |
| AKT1 | Akt | AGC | 6npz | B | B | - | Human | Show | |
| AKT1 | Akt | AGC | 6s9w | A | A | ~{n}-[3-[1-[[4-(5-methyl-6-oxidanylidene-3-phenyl-1~{h}-pyrazin-2-yl)phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | Show | |
| AKT1 | Akt | AGC | 6s9w | A | B | ~{n}-[3-[1-[[4-(5-methyl-6-oxidanylidene-3-phenyl-1~{h}-pyrazin-2-yl)phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | Show | |
| AKT1 | Akt | AGC | 6s9x | A | ~{n}-[3-[1-[[4-[5-[(4-hydroxyphenyl)methyl]-6-oxidanylidene-2-phenyl-1~{h}-pyrazin-3-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | Show | | |
| AKT1 | Akt | AGC | 7apj | A | - | Human | Show | | |
| AKT1 | Akt | AGC | 7nh4 | A | A | ~{n}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | Show | |
| AKT1 | Akt | AGC | 7nh4 | A | B | ~{n}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | Show | |
| AKT1 | Akt | AGC | 7nh5 | A | A | ~{n}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{h}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide | Human | Show | |
| AKT1 | Akt | AGC | 7nh5 | A | B | ~{n}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{h}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide | Human | Show | |
| AKT1 | Akt | AGC | 8uvy | A | A | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | Show | |
| AKT1 | Akt | AGC | 8uvy | A | B | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | Show | |
| AKT1 | Akt | AGC | 8uw2 | A | A | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | Show | |
| AKT1 | Akt | AGC | 8uw2 | A | B | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | Show | |
| AKT1 | Akt | AGC | 8uw7 | A | A | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | Show | |
| AKT1 | Akt | AGC | 8uw7 | A | B | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | Show | |
| AKT1 | Akt | AGC | 8uw9 | A | A | n-({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)-2-(2-fluoro-4-formyl-3-hydroxyphenyl)acetamide | Human | Show | |
| AKT1 | Akt | AGC | 8uw9 | A | B | n-({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)-2-(2-fluoro-4-formyl-3-hydroxyphenyl)acetamide | Human | Show | |
| AKT2 | Akt | AGC | 1gzk | A | - | Human | Show | | |
| AKT2 | Akt | AGC | 1gzn | A | - | Human | Show | | |
| AKT2 | Akt | AGC | 1gzo | A | - | Human | Show | | |
| AKT2 | Akt | AGC | 1mrv | A | - | Human | Show | | |
| AKT2 | Akt | AGC | 1mry | A | - | Human | Show | | |
| AKT2 | Akt | AGC | 1o6k | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| AKT2 | Akt | AGC | 1o6l | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| AKT2 | Akt | AGC | 2jdo | A | isoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)amide | Human | Show | | |
| AKT2 | Akt | AGC | 2jdr | A | (2s)-1-(1h-indol-3-yl)-3-{[5-(3-methyl-1h-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine | Human | Show | | |
| AKT2 | Akt | AGC | 2uw9 | A | 4-(4-chlorophenyl)-4-[4-(1h-pyrazol-4-yl)phenyl]piperidine | Human | Show | | |
| AKT2 | Akt | AGC | 2x39 | A | 4-amino-n-(4-chlorobenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide | Human | Show | | |
| AKT2 | Akt | AGC | 2xh5 | A | 4-(4-tert-butylbenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium | Human | Show | | |
| AKT2 | Akt | AGC | 3d0e | A | 4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3s)-piperidin-3-ylmethoxy]-1h-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-ol | Human | Show | | |
| AKT2 | Akt | AGC | 3d0e | B | 4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3s)-piperidin-3-ylmethoxy]-1h-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-ol | Human | Show | | |
| AKT2 | Akt | AGC | 3e87 | A | A | n-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide | Human | Show | |
