PDB-code
Browse kinase entries (page 110 of 282)
First 106 107 108 PreviousLast114 113 112 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | EGFR | EGFR | TK | 8kfq | A | ~{n}-[3-[[6-chloranyl-2-[(1-ethylpyrazol-4-yl)amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide | Human | Show |  | |
| EGFR | EGFR | TK | 8sc7 | A | A | n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide | Human | Show | |
| EGFR | EGFR | TK | 8sc7 | A | B | n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide | Human | Show | |
| EGFR | EGFR | TK | 8sc7 | A | C | n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide | Human | Show | |
| EGFR | EGFR | TK | 8tjl | A | 1-{3-[(4-amino-1-tert-butyl-1h-pyrazolo[3,4-d]pyrimidin-3-yl)oxy]azetidin-1-yl}propan-1-one | Human | Show | | |
| EGFR | EGFR | TK | 8to3 | A | A | 3-hydroxy-n-{(3p)-3-[(4p)-2-(methylsulfanyl)-5-{2-[4-(piperazin-1-yl)anilino]pyridin-4-yl}-1h-imidazol-4-yl]phenyl}-2-[(1-oxo-1,3-dihydro-2h-isoindol-2-yl)methyl]benzamide | Human | Show | |
| EGFR | EGFR | TK | 8to3 | A | B | 3-hydroxy-n-{(3p)-3-[(4p)-2-(methylsulfanyl)-5-{2-[4-(piperazin-1-yl)anilino]pyridin-4-yl}-1h-imidazol-4-yl]phenyl}-2-[(1-oxo-1,3-dihydro-2h-isoindol-2-yl)methyl]benzamide | Human | Show | |
| EGFR | EGFR | TK | 8to4 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 8to4 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 8wd4 | A | ~{n}-[3,3-bis(fluoranyl)propyl]-4-[[(2~{s})-butan-2-yl]amino]-6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]pyridine-3-carboxamide | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 2a19 | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 2a19 | C | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 2a1a | B | - | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 3uiu | A | - | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 3uiu | B | - | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 6d3k | A | adenosine-5'-diphosphate | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 6d3k | B | adenosine-5'-diphosphate | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 6d3k | C | adenosine-5'-diphosphate | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 6d3l | A | - | Human | Show | | |
| EIF2AK2 (PKR) | PEK | Other | 8qel | B | (3~{z})-3-[(4-methyl-1~{h}-imidazol-5-yl)methylidene]-2-oxidanylidene-1~{h}-indole-5-carboxamide | Human | Show | | |
| Eif2ak3 (PEK) | PEK | Other | 3qd2 | B | - | Mouse | Show | | |
| EIF2AK3 (PEK) | PEK | Other | 4g31 | A | A | 1-[5-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4g31 | A | B | 1-[5-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4g34 | A | A | 1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydro-1h-indol-1-yl]-2-phenylethanone | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4g34 | A | B | 1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydro-1h-indol-1-yl]-2-phenylethanone | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4m7i | A | 1-[5-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-1h-indol-1-yl]-2-(6-methylpyridin-2-yl)ethanone | Human | Show | | |
| EIF2AK3 (PEK) | PEK | Other | 4x7h | A | A | n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7h | A | B | n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7j | A | A | 2-amino-n-[4-methoxy-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7j | A | B | 2-amino-n-[4-methoxy-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7k | A | A | 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7k | A | B | 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7l | A | A | 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7l | A | B | 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7n | A | A | 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7n | A | B | 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7o | A | A | 1-[5-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 4x7o | A | B | 1-[5-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 7mf0 | A | 2-amino-n-cyclopropyl-5-(4-{[(2r)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino}-2-methylphenyl)pyridine-3-carboxamide | Human | Show | | |
| EIF2AK3 (PEK) | PEK | Other | 8eq9 | A | A | (2r)-n-[(4m)-4-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-(3-fluorophenyl)-2-hydroxyacetamide | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 8eq9 | A | B | (2r)-n-[(4m)-4-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-(3-fluorophenyl)-2-hydroxyacetamide | Human | Show | |
| EIF2AK3 (PEK) | PEK | Other | 8eqd | A | (2r)-n-[(4m)-4-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-(3-fluorophenyl)-2-hydroxyacetamide | Human | Show | | |
| EIF2AK3 (PEK) | PEK | Other | 8eqe | A | (2r)-n-[(4m)-4-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-hydroxy-2-[3-(trifluoromethyl)phenyl]acetamide | Human | Show | | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | A | A | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | Show | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | A | B | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | Show | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | B | A | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | Show | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | B | B | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | Show | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3n | A | n-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-2,5-dichloro-3-(hydroxymethyl)benzene-1-sulfonamide | Human | Show | | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3o | A | n-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-5-chloro-2-methoxypyridine-3-sulfonamide | Human | Show | | |
| EIF2AK4 (GCN2) | PEK | Other | 7qq6 | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | Show | |
