PDB-code
Browse kinase entries (page 136 of 282)
First 132 133 134 PreviousLast140 139 138 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | HCK | Src | TK | 4lue | B | 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show |  | |
| HCK | Src | TK | 5h09 | A | ethyl (2~{s})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-4-methyl-pentanoate | Human | Show | | |
| HCK | Src | TK | 5h0b | A | (2~{s})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]azaniumyl]-4-methyl-pentanoate | Human | Show | | |
| HCK | Src | TK | 5h0e | A | (2~{s})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-4-methyl-pentanamide | Human | Show | | |
| HCK | Src | TK | 5h0g | A | (2~{s})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-~{n},4-dimethyl-pentanamide | Human | Show | | |
| HCK | Src | TK | 5h0h | A | (2~{s})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-~{n},~{n},4-trimethyl-pentanamide | Human | Show | | |
| HCK | Src | TK | 5zj6 | A | 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | | |
| HCK | Src | TK | 5zj6 | B | 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | | |
| HIPK2 | DYRK | CMGC | 6p5s | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | Show | |
| HIPK2 | DYRK | CMGC | 6p5s | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | Show | |
| HIPK2 | DYRK | CMGC | 7ncf | A | 3-(4-tert-butylphenyl)-5-(1h-pyrazol-4-yl)furo[3,2-b]pyridine | Human | Show | | |
| HIPK3 | DYRK | CMGC | 7o7i | A | - | Human | Show | | |
| HIPK3 | DYRK | CMGC | 7o7j | A | n-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1h-benzimidazol-6-yl]pyrimidin-2-amine | Human | Show | | |
| Igf1r (IGF1R) | InsR | TK | 6pyh | A | - | Mouse | Show | | |
| Igf1r (IGF1R) | InsR | TK | 6pyh | D | - | Mouse | Show | | |
| IGF1R | InsR | TK | 1jqh | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IGF1R | InsR | TK | 1jqh | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IGF1R | InsR | TK | 1jqh | C | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IGF1R | InsR | TK | 1k3a | A | phosphomethylphosphonic acid adenylate ester | Human | Show | | |
| IGF1R | InsR | TK | 1m7n | A | - | Human | Show | | |
| IGF1R | InsR | TK | 1m7n | B | - | Human | Show | | |
| IGF1R | InsR | TK | 1p4o | A | - | Human | Show | | |
| IGF1R | InsR | TK | 1p4o | B | - | Human | Show | | |
| IGF1R | InsR | TK | 2oj9 | A | 3-[5-(1h-imidazol-1-yl)-7-methyl-1h-benzimidazol-2-yl]-4-[(pyridin-2-ylmethyl)amino]pyridin-2(1h)-one | Human | Show | | |
| IGF1R | InsR | TK | 2zm3 | A | (4z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2h,4h)-dione | Human | Show | | |
| IGF1R | InsR | TK | 2zm3 | B | (4z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2h,4h)-dione | Human | Show | | |
| IGF1R | InsR | TK | 2zm3 | C | (4z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2h,4h)-dione | Human | Show | | |
| IGF1R | InsR | TK | 2zm3 | D | (4z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2h,4h)-dione | Human | Show | | |
| IGF1R | InsR | TK | 3d94 | A | A | 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine | Human | Show | |
| IGF1R | InsR | TK | 3d94 | A | B | 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine | Human | Show | |
| IGF1R | InsR | TK | 3f5p | A | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | B | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | C | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | D | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | E | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | F | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | G | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | H | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | I | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | J | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | K | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | L | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | M | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | R | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | S | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3f5p | T | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | Human | Show | | |
| IGF1R | InsR | TK | 3i81 | A | 1-{4-[(3-cyclopropyl-1h-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-n-(6-fluoropyridin-3-yl)-2-methyl-l-prolinamide | Human | Show | | |
| IGF1R | InsR | TK | 3lvp | A | 3-(4-chloro-1h-pyrrolo[2,3-b]pyridin-2-yl)-5,6-dimethoxy-1-methyl-1h-pyrrolo[3,2-b]pyridine | Human | Show | | |
| IGF1R | InsR | TK | 3lvp | B | 3-(4-chloro-1h-pyrrolo[2,3-b]pyridin-2-yl)-5,6-dimethoxy-1-methyl-1h-pyrrolo[3,2-b]pyridine | Human | Show | | |
| IGF1R | InsR | TK | 3lvp | C | 3-(4-chloro-1h-pyrrolo[2,3-b]pyridin-2-yl)-5,6-dimethoxy-1-methyl-1h-pyrrolo[3,2-b]pyridine | Human | Show | |
