PDB-code
Browse kinase entries (page 21 of 282)
First 17 18 19 PreviousLast25 24 23 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | AURKA (AurA) | Aur | Other | 8sso | A | B | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | Show |  |
| AURKA (AurA) | Aur | Other | 8sso | A | C | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | Show | |
| AURKA (AurA) | Aur | Other | 8ssp | A | A | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | Show | |
| AURKA (AurA) | Aur | Other | 8ssp | A | B | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | Show | |
| AURKB (AurB) | Aur | Other | 4af3 | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | Show | | |
| AURKC (AurC) | Aur | Other | 6gr8 | A | A | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | Show | |
| AURKC (AurC) | Aur | Other | 6gr8 | A | B | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | Show | |
| AURKC (AurC) | Aur | Other | 6gr9 | A | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | Show | |
| AURKC (AurC) | Aur | Other | 6gr9 | A | B | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | Show | |
| AXL | Axl | TK | 5u6b | A | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | Show | | |
| AXL | Axl | TK | 5u6b | B | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | Show | | |
| AXL | Axl | TK | 5u6b | C | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | Show | | |
| AXL | Axl | TK | 5u6b | D | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | Show | | |
| BMP2K (BIKE) | NAK | Other | 4w9w | A | A | 5-(3-fluorophenyl)-n-[(3s)-3-piperidyl]-3-ureido-thiophene-2-carboxamide | Human | Show | |
| BMP2K (BIKE) | NAK | Other | 4w9w | A | B | 5-(3-fluorophenyl)-n-[(3s)-3-piperidyl]-3-ureido-thiophene-2-carboxamide | Human | Show | |
| BMP2K (BIKE) | NAK | Other | 4w9x | A | baricitinib | Human | Show | | |
| BMP2K (BIKE) | NAK | Other | 5i3o | A | n-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | Show | | |
| BMP2K (BIKE) | NAK | Other | 5i3o | B | n-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | Show | | |
| BMP2K (BIKE) | NAK | Other | 5i3r | A | n-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1h-indazol-3-yl]cyclopropanecarboxamide | Human | Show | | |
| BMP2K (BIKE) | NAK | Other | 5i3r | B | n-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1h-indazol-3-yl]cyclopropanecarboxamide | Human | Show | | |
| BMP2K (BIKE) | NAK | Other | 5ikw | A | n-(6-{3-[(cyclopropylsulfonyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | Show | | |
| BMPR1B | STKR | TKL | 3mdy | A | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| BMPR1B | STKR | TKL | 3mdy | A | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| BMPR1B | STKR | TKL | 3mdy | C | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| BMPR1B | STKR | TKL | 3mdy | C | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| BMPR2 | STKR | TKL | 3g2f | A | A | adenosine-5'-diphosphate | Human | Show | |
| BMPR2 | STKR | TKL | 3g2f | A | B | adenosine-5'-diphosphate | Human | Show | |
| BMPR2 | STKR | TKL | 3g2f | B | A | adenosine-5'-diphosphate | Human | Show | |
| BMPR2 | STKR | TKL | 3g2f | B | B | adenosine-5'-diphosphate | Human | Show | |
| BMPR2 | STKR | TKL | 6unp | A | A | adenosine-5'-diphosphate | Human | Show | |
| BMPR2 | STKR | TKL | 6unp | A | B | adenosine-5'-diphosphate | Human | Show | |
| BMX | Tec | TK | 3sxr | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | | |
| BMX | Tec | TK | 3sxr | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | | |
| BMX | Tec | TK | 3sxs | A | 1-tert-butyl-3-(4-chloro-phenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine | Human | Show | | |
| BMX | Tec | TK | 6i99 | A | ~{n}-[2-methyl-5-[8-[4-(methylsulfonylamino)phenyl]-2-oxidanylidene-benzo[h][1,6]naphthyridin-1-yl]phenyl]-3-oxidanyl-propanamide | Human | Show | | |
| BMX | Tec | TK | 6i99 | B | ~{n}-[2-methyl-5-[8-[4-(methylsulfonylamino)phenyl]-2-oxidanylidene-benzo[h][1,6]naphthyridin-1-yl]phenyl]-3-oxidanyl-propanamide | Human | Show | | |
| BMX | Tec | TK | 8x2a | A | A | 4-[(3s)-3-{[(2e)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1h-indole-7-carboxamide | Human | Show | |
| BMX | Tec | TK | 8x2a | A | B | 4-[(3s)-3-{[(2e)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1h-indole-7-carboxamide | Human | Show | |
| BRAF | RAF | TKL | 1uwh | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | Show | | |
| BRAF | RAF | TKL | 1uwh | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | Show | | |
| BRAF | RAF | TKL | 1uwj | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | Show | | |
| BRAF | RAF | TKL | 1uwj | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | Show | | |
| BRAF | RAF | TKL | 2fb8 | A | (1z)-5-(2-{4-[2-(dimethylamino)ethoxy]phenyl}-5-pyridin-4-yl-1h-imidazol-4-yl)indan-1-one oxime | Human | Show | | |
| BRAF | RAF | TKL | 2fb8 | B | (1z)-5-(2-{4-[2-(dimethylamino)ethoxy]phenyl}-5-pyridin-4-yl-1h-imidazol-4-yl)indan-1-one oxime | Human | Show | | |
| BRAF | RAF | TKL | 3c4c | A | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 3c4c | B | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | Show | | |
| BRAF | RAF | TKL | 3d4q | A | (1e)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime | Human | Show | | |
| BRAF | RAF | TKL | 3d4q | B | (1e)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime | Human | Show | | |
| BRAF | RAF | TKL | 3idp | A | n~1~-(4-chlorophenyl)-6-methyl-n~5~-[3-(7h-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine | Human | Show | | |
| BRAF | RAF | TKL | 3idp | B | n~1~-(4-chlorophenyl)-6-methyl-n~5~-[3-(7h-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine | Human | Show | |
