PDB-code
Browse kinase entries (page 244 of 282)
First 240 241 242 PreviousLast248 247 246 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | PTK2B (PYK2) | FAK | TK | 4h1m | A | 7-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)-n-(propan-2-yl)-1h-indole-2-carboxamide | Human | Show |  | |
| PTK2B (PYK2) | FAK | TK | 5to8 | A | 25-(methylsulfonyl)-8-(trifluoromethyl)-5,17,18,21,22,23,24,25-octahydro-12h-7,11-(azeno)-16,13-(metheno)pyrido[3,2-i]pyrrolo[1,2-q][1,3,7,11,17]pentaazacyclohenicosin-20(6h)-one | Human | Show | | |
| PTK2B (PYK2) | FAK | TK | 5tob | A | n-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | Human | Show | | |
| PTK2B (PYK2) | FAK | TK | 8xox | A | A | n-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | Human | Show | |
| PTK2B (PYK2) | FAK | TK | 8xox | A | B | n-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | Human | Show | |
| PTK2B (PYK2) | FAK | TK | 8ygx | A | A | - | Human | Show | |
| PTK2B (PYK2) | FAK | TK | 8ygx | A | B | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | A | A | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | A | B | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | B | A | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | B | B | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | C | A | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | C | B | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | D | A | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5d7v | D | B | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 5da3 | A | A | (2-chloro-4-{[6-cyclopropyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | Show | |
| PTK6 (BRK) | Src | TK | 5da3 | A | B | (2-chloro-4-{[6-cyclopropyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | B | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | B | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | C | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | C | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | D | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 5h2u | D | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 6cz2 | A | A | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 6cz2 | A | B | - | Human | Show | |
| PTK6 (BRK) | Src | TK | 6cz3 | A | A | (3-fluoro-4-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | Show | |
| PTK6 (BRK) | Src | TK | 6cz3 | A | B | (3-fluoro-4-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | Show | |
| PTK6 (BRK) | Src | TK | 6cz4 | A | A | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide | Human | Show | |
| PTK6 (BRK) | Src | TK | 6cz4 | A | B | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide | Human | Show | |
| PTK7 (CCK4) | CCK4 | TK | 6vg3 | A | - | Human | Show | | |
| PTK7 (CCK4) | CCK4 | TK | 6vg3 | B | - | Human | Show | | |
| PTK7 (CCK4) | CCK4 | TK | 6vg3 | C | - | Human | Show | | |
| RAF1 | RAF | TKL | 3omv | A | (1e)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime | Human | Show | | |
| RAF1 | RAF | TKL | 3omv | B | (1e)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime | Human | Show | | |
| RAF1 | RAF | TKL | 8chf | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | Show | | |
| RAF1 | RAF | TKL | 8cpd | A | - | Human | Show | | |
| RAF1 | RAF | TKL | 8gae | D | - | Human | Show | | |
| RAF1 | RAF | TKL | 8gft | D | - | Human | Show | | |
| RAF1 | RAF | TKL | 8u1l | C | - | Human | Show | | |
| RET | Ret | TK | 2ivs | A | A | (3ar,4r,6r,6ar)-4-(6-amino-9h-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-ol 2-oxide | Human | Show | |
| RET | Ret | TK | 2ivs | A | B | (3ar,4r,6r,6ar)-4-(6-amino-9h-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-ol 2-oxide | Human | Show | |
| RET | Ret | TK | 2ivs | B | A | (3ar,4r,6r,6ar)-4-(6-amino-9h-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-ol 2-oxide | Human | Show | |
| RET | Ret | TK | 2ivs | B | B | (3ar,4r,6r,6ar)-4-(6-amino-9h-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-ol 2-oxide | Human | Show | |
| RET | Ret | TK | 2ivt | A | A | adenosine monophosphate | Human | Show | |
| RET | Ret | TK | 2ivt | A | B | adenosine monophosphate | Human | Show | |
| RET | Ret | TK | 2ivu | A | 4-bromo-2-fluoro-n-[(4e)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4(1h)-ylidene]aniline | Human | Show | | |
| RET | Ret | TK | 2ivv | A | 1-ter-butyl-3-p-tolyl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine | Human | Show | | |
| RET | Ret | TK | 2x2k | A | A | (3z)-5-amino-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-one | Human | Show | |
