PDB-code
Browse kinase entries (page 147 of 282)
First 143 144 145 PreviousLast151 150 149 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | ITK | Tec | TK | 4ppc | B | B | n-{1-[(1r)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show |  |
| ITK | Tec | TK | 4pqn | A | A | n-{1-[(1s)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6,6-dimethyl-4,5,6,7-tetrahydro-1h-indazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4pqn | A | B | n-{1-[(1s)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6,6-dimethyl-4,5,6,7-tetrahydro-1h-indazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4qd6 | A | A | trans-4-({6-[(5-phenyl-1h-pyrazol-3-yl)amino]-4-(phenylsulfonyl)pyridin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4qd6 | A | B | trans-4-({6-[(5-phenyl-1h-pyrazol-3-yl)amino]-4-(phenylsulfonyl)pyridin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4qd6 | B | A | trans-4-({6-[(5-phenyl-1h-pyrazol-3-yl)amino]-4-(phenylsulfonyl)pyridin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4qd6 | B | B | trans-4-({6-[(5-phenyl-1h-pyrazol-3-yl)amino]-4-(phenylsulfonyl)pyridin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4rfm | A | A | (4as,5ar)-n-{1-[(r)-[(2r)-1,1-dioxidotetrahydro-2h-thiopyran-2-yl](phenyl)methyl]-1h-pyrazol-4-yl}-5,5-difluoro-5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4rfm | A | B | (4as,5ar)-n-{1-[(r)-[(2r)-1,1-dioxidotetrahydro-2h-thiopyran-2-yl](phenyl)methyl]-1h-pyrazol-4-yl}-5,5-difluoro-5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indazole-3-carboxamide | Human | Show | |
| Jak1 (JAK1) | JakA | TK | 8ewy | A | - | Mouse | Show | | |
| JAK1 | JakA | TK | 3eyg | A | A | 3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | Human | Show | |
| JAK1 | JakA | TK | 3eyg | A | B | 3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | Human | Show | |
| JAK1 | JakA | TK | 3eyh | A | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | | |
| JAK1 | JakA | TK | 4e4l | A | A | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4e4l | A | B | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4e4l | B | A | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4e4l | B | B | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4e4l | D | A | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4e4l | D | B | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4e4l | E | A | - | Human | Show | |
| JAK1 | JakA | TK | 4e4l | E | B | - | Human | Show | |
| JAK1 | JakA | TK | 4e4n | A | tert-butyl [(1r,3r)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)cyclopentyl]carbamate | Human | Show | | |
| JAK1 | JakA | TK | 4e4n | B | tert-butyl [(1r,3r)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)cyclopentyl]carbamate | Human | Show | | |
| JAK1 | JakA | TK | 4e5w | A | A | [4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl][(2s)-1-(propan-2-yl)pyrrolidin-2-yl]methanone | Human | Show | |
| JAK1 | JakA | TK | 4e5w | A | B | [4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl][(2s)-1-(propan-2-yl)pyrrolidin-2-yl]methanone | Human | Show | |
| JAK1 | JakA | TK | 4e5w | B | A | [4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl][(2s)-1-(propan-2-yl)pyrrolidin-2-yl]methanone | Human | Show | |
| JAK1 | JakA | TK | 4e5w | B | B | [4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl][(2s)-1-(propan-2-yl)pyrrolidin-2-yl]methanone | Human | Show | |
| JAK1 | JakA | TK | 4ehz | A | A | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ehz | A | B | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ehz | B | A | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ehz | B | B | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ehz | C | A | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ehz | C | B | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ehz | D | A | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ehz | D | B | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | |
| JAK1 | JakA | TK | 4ei4 | A | (1r,3r)-3-(2-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(8h)-yl)cyclohexanol | Human | Show | | |
| JAK1 | JakA | TK | 4ei4 | B | (1r,3r)-3-(2-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(8h)-yl)cyclohexanol | Human | Show | | |
| JAK1 | JakA | TK | 4fk6 | A | A | n-({1-[(1r,2r,4s)-bicyclo[2.2.1]hept-2-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl}methyl)methanesulfonamide | Human | Show | |
| JAK1 | JakA | TK | 4fk6 | A | B | n-({1-[(1r,2r,4s)-bicyclo[2.2.1]hept-2-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl}methyl)methanesulfonamide | Human | Show | |
| JAK1 | JakA | TK | 4fk6 | B | A | n-({1-[(1r,2r,4s)-bicyclo[2.2.1]hept-2-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl}methyl)methanesulfonamide | Human | Show | |
| JAK1 | JakA | TK | 4fk6 | B | B | n-({1-[(1r,2r,4s)-bicyclo[2.2.1]hept-2-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl}methyl)methanesulfonamide | Human | Show | |
| JAK1 | JakA | TK | 4i5c | A | A | 3-oxo-3-[(3r)-3-(pyrrolo[2,3-b][1,2,3]triazolo[4,5-d]pyridin-1(6h)-yl)piperidin-1-yl]propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4i5c | A | B | 3-oxo-3-[(3r)-3-(pyrrolo[2,3-b][1,2,3]triazolo[4,5-d]pyridin-1(6h)-yl)piperidin-1-yl]propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4i5c | B | A | 3-oxo-3-[(3r)-3-(pyrrolo[2,3-b][1,2,3]triazolo[4,5-d]pyridin-1(6h)-yl)piperidin-1-yl]propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4i5c | B | B | 3-oxo-3-[(3r)-3-(pyrrolo[2,3-b][1,2,3]triazolo[4,5-d]pyridin-1(6h)-yl)piperidin-1-yl]propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivb | A | A | trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexanecarbonitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivb | A | B | trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexanecarbonitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivb | B | A | trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexanecarbonitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivb | B | B | trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexanecarbonitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivc | A | (trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexyl)acetonitrile | Human | Show | |
