PDB-code
Browse kinase entries (page 222 of 282)
First 218 219 220 PreviousLast226 225 224 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | PIK3CA (p110a) | PIK | Atypical | 7mlk | A | B | 4-[6-(3,4,5-trimethoxyanilino)pyrazin-2-yl]benzamide | Human | Show |  |
| PIK3CA (p110a) | PIK | Atypical | 7myn | A | A | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7myn | A | B | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7myo | B | A | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7myo | B | B | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7pg5 | A | A | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7pg5 | A | B | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7pg6 | A | A | (2s)-n~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7pg6 | A | B | (2s)-n~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7r9v | A | n-[2-(4-{4-[2-amino-4-(difluoromethyl)pyrimidin-5-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}piperazin-1-yl)-2-oxoethyl]-1-(prop-2-enoyl)piperidine-4-carboxamide | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 7r9y | A | n-[2-(4-{4-[2-amino-4-(difluoromethyl)pyrimidin-5-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}piperazin-1-yl)-2-oxoethyl]-n-methyl-1-(prop-2-enoyl)piperidine-4-carboxamide | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 7tz7 | A | A | (4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-one | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 7tz7 | A | B | (4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-one | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8am0 | A | (2r)-2-[[2-[(4s)-4-[bis(fluoranyl)methyl]-2-oxidanylidene-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8bfu | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8dcp | A | A | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8dcp | A | B | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8dcx | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8dd4 | A | A | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8dd4 | A | B | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8dd8 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8exl | A | A | 2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1h-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-1h-pyrazol-1-yl)propanamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8exl | A | B | 2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1h-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-1h-pyrazol-1-yl)propanamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8exo | A | A | 1-{(4s,11am)-2-[(4r)-2-oxo-4-(propan-2-yl)-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-prolinamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8exo | A | B | 1-{(4s,11am)-2-[(4r)-2-oxo-4-(propan-2-yl)-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-prolinamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8exu | A | A | (2s)-2-cyclopropyl-2-({(4s,11am)-2-[(4s)-2-oxo-4-(trifluoromethyl)-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}amino)acetamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8exu | A | B | (2s)-2-cyclopropyl-2-({(4s,11am)-2-[(4s)-2-oxo-4-(trifluoromethyl)-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}amino)acetamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8exv | A | A | n~2~-{(4s,11ap)-2-[(4s)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-alaninamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8exv | A | B | n~2~-{(4s,11ap)-2-[(4s)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-alaninamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8gua | A | (2s)-n~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8gub | A | (2s)-n~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8gud | A | A | (2s)-n~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8ilr | A | B | n-[(2s)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8ils | A | B | n-[(2r)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8ilv | A | n-[(2r)-1-(ethylamino)-1-oxidanylidene-3-[3-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8ow2 | A | A | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8ow2 | A | B | - | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8sbc | A | A | (2m)-7-[(3r)-3-methylmorpholin-4-yl]-5-[(3s)-3-methylmorpholin-4-yl]-2-(pyridin-2-yl)-1h-imidazo[4,5-b]pyridine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8sbc | A | B | (2m)-7-[(3r)-3-methylmorpholin-4-yl]-5-[(3s)-3-methylmorpholin-4-yl]-2-(pyridin-2-yl)-1h-imidazo[4,5-b]pyridine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8sbj | A | A | (2m)-7-[(3r)-3-methylmorpholin-4-yl]-5-[(3s)-3-methylmorpholin-4-yl]-2-(1h-pyrazol-3-yl)-3h-imidazo[4,5-b]pyridine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8sbj | A | B | (2m)-7-[(3r)-3-methylmorpholin-4-yl]-5-[(3s)-3-methylmorpholin-4-yl]-2-(1h-pyrazol-3-yl)-3h-imidazo[4,5-b]pyridine | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8tdu | A | A | n~2~-{(4s,11ap)-2-[(4s)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-alaninamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8tdu | A | B | n~2~-{(4s,11ap)-2-[(4s)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-alaninamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8tgd | A | A | n~2~-{(4s,11ap)-2-[(4s)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-alaninamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8tgd | A | B | n~2~-{(4s,11ap)-2-[(4s)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-l-alaninamide | Human | Show | |
| PIK3CA (p110a) | PIK | Atypical | 8ts7 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8ts8 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8ts9 | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8tsa | A | - | Human | Show | | |
| PIK3CA (p110a) | PIK | Atypical | 8tsb | A | - | Human | Show | |
