PDB-code
Browse kinase entries (page 100 of 282)
First 96 97 98 PreviousLast104 103 102 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | EGFR | EGFR | TK | 3ika | A | A | n-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | Show |  |
| EGFR | EGFR | TK | 3ika | A | B | n-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | Show | |
| EGFR | EGFR | TK | 3ika | B | A | - | Human | Show | |
| EGFR | EGFR | TK | 3ika | B | B | - | Human | Show | |
| EGFR | EGFR | TK | 3lzb | A | n-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide | Human | Show | | |
| EGFR | EGFR | TK | 3lzb | B | n-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide | Human | Show | | |
| EGFR | EGFR | TK | 3lzb | C | n-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide | Human | Show | | |
| EGFR | EGFR | TK | 3lzb | D | n-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide | Human | Show | | |
| EGFR | EGFR | TK | 3poz | A | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide | Human | Show | | |
| EGFR | EGFR | TK | 3ug1 | A | A | - | Human | Show | |
| EGFR | EGFR | TK | 3ug1 | A | B | - | Human | Show | |
| EGFR | EGFR | TK | 3ug2 | A | A | gefitinib | Human | Show | |
| EGFR | EGFR | TK | 3ug2 | A | B | gefitinib | Human | Show | |
| EGFR | EGFR | TK | 3vjn | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| EGFR | EGFR | TK | 3vjo | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| EGFR | EGFR | TK | 3w2o | A | A | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide | Human | Show | |
| EGFR | EGFR | TK | 3w2o | A | B | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide | Human | Show | |
| EGFR | EGFR | TK | 3w2p | A | A | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-4-(dimethylamino)butanamide | Human | Show | |
| EGFR | EGFR | TK | 3w2p | A | B | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-4-(dimethylamino)butanamide | Human | Show | |
| EGFR | EGFR | TK | 3w2q | A | A | n-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide | Human | Show | |
| EGFR | EGFR | TK | 3w2q | A | B | n-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide | Human | Show | |
| EGFR | EGFR | TK | 3w2r | A | A | 1-{3-[2-chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5h-pyrrolo[3,2-d]pyrimidin-4-yl}amino)phenoxy]phenyl}-3-cyclohexylurea | Human | Show | |
| EGFR | EGFR | TK | 3w2r | A | B | 1-{3-[2-chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5h-pyrrolo[3,2-d]pyrimidin-4-yl}amino)phenoxy]phenyl}-3-cyclohexylurea | Human | Show | |
| EGFR | EGFR | TK | 3w2s | A | A | 1-{3-[2-chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5h-pyrrolo[3,2-d]pyrimidin-4-yl}amino)phenoxy]phenyl}-3-cyclohexylurea | Human | Show | |
| EGFR | EGFR | TK | 3w2s | A | B | 1-{3-[2-chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5h-pyrrolo[3,2-d]pyrimidin-4-yl}amino)phenoxy]phenyl}-3-cyclohexylurea | Human | Show | |
| EGFR | EGFR | TK | 3w32 | A | 4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-n-[2-(methylsulfonyl)ethyl]-8,9-dihydro-7h-pyrimido[4,5-b]azepine-6-carboxamide | Human | Show | | |
| EGFR | EGFR | TK | 3w33 | A | A | 4-{[4-(1-benzothiophen-4-yloxy)-3-chlorophenyl]amino}-n-(2-hydroxyethyl)-8,9-dihydro-7h-pyrimido[4,5-b]azepine-6-carboxamide | Human | Show | |
| EGFR | EGFR | TK | 3w33 | A | B | 4-{[4-(1-benzothiophen-4-yloxy)-3-chlorophenyl]amino}-n-(2-hydroxyethyl)-8,9-dihydro-7h-pyrimido[4,5-b]azepine-6-carboxamide | Human | Show | |
| EGFR | EGFR | TK | 4g5j | A | A | n-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide | Human | Show | |
| EGFR | EGFR | TK | 4g5j | A | B | n-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide | Human | Show | |
| EGFR | EGFR | TK | 4g5p | A | n-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide | Human | Show | | |
| EGFR | EGFR | TK | 4g5p | B | - | Human | Show | | |
| EGFR | EGFR | TK | 4hjo | A | [6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amine | Human | Show | | |
| EGFR | EGFR | TK | 4i1z | A | A | - | Human | Show | |
| EGFR | EGFR | TK | 4i1z | A | B | - | Human | Show | |
| EGFR | EGFR | TK | 4i20 | A | - | Human | Show | | |
| EGFR | EGFR | TK | 4i21 | A | - | Human | Show | | |
| EGFR | EGFR | TK | 4i21 | B | - | Human | Show | | |
| EGFR | EGFR | TK | 4i22 | A | gefitinib | Human | Show | | |
| EGFR | EGFR | TK | 4i23 | A | (2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide | Human | Show | | |
| EGFR | EGFR | TK | 4i24 | A | (2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide | Human | Show | | |
| EGFR | EGFR | TK | 4i24 | B | (2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide | Human | Show | | |
| EGFR | EGFR | TK | 4jq7 | A | (2s)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol | Human | Show | | |
| EGFR | EGFR | TK | 4jq8 | A | n-[3-(4-{[(1s)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]-n~3~,n~3~-dimethyl-beta-alaninamide | Human | Show | | |
| EGFR | EGFR | TK | 4jr3 | A | n-[3-(4-{[(1s)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]acetamide | Human | Show | | |
| EGFR | EGFR | TK | 4jrv | A | 4-(dimethylamino)-n-[3-(4-{[(1s)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]butanamide | Human | Show | | |
| EGFR | EGFR | TK | 4li5 | A | A | n-(3-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide | Human | Show | |
| EGFR | EGFR | TK | 4li5 | A | B | n-(3-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide | Human | Show | |
| EGFR | EGFR | TK | 4ll0 | A | n-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamide | Human | Show | | |
| EGFR | EGFR | TK | 4ll0 | B | n-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamide | Human | Show | |
