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Updated: 05-Nov-2025

Browse kinase entries (page 213 of 282)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
PAK1STE20STE4zloBB-HumanShow
PAK1STE20STE4zy4A2-(4-aminopiperidin-1-yl)-n-(5-cyclopropyl-1h-pyrazol-3-yl)thieno[3,2-d]pyrimidin-4-amineHumanShow
PAK1STE20STE4zy4B2-(4-aminopiperidin-1-yl)-n-(5-cyclopropyl-1h-pyrazol-3-yl)thieno[3,2-d]pyrimidin-4-amineHumanShow
PAK1STE20STE4zy5An~2~-[(trans-4-aminocyclohexyl)methyl]-n~4~-(3-cyclopropyl-1h-pyrazol-5-yl)pyrimidine-2,4-diamineHumanShow
PAK1STE20STE4zy5Bn~2~-[(trans-4-aminocyclohexyl)methyl]-n~4~-(3-cyclopropyl-1h-pyrazol-5-yl)pyrimidine-2,4-diamineHumanShow
PAK1STE20STE4zy6AAn~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamineHumanShow
PAK1STE20STE4zy6ABn~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamineHumanShow
PAK1STE20STE4zy6BAn~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamineHumanShow
PAK1STE20STE4zy6BBn~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamineHumanShow
PAK1STE20STE5dewA8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5dewB8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5deyA8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5deyB8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5dfpAA6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5dfpAB6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5imeA8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5imeB8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
PAK1STE20STE5kbqA[4-methyl-3-[methyl-[2-[(3-methylsulfonyl-5-morpholin-4-yl-phenyl)amino]pyrimidin-4-yl]amino]phenyl]methanolHumanShow
PAK1STE20STE5kbqB-HumanShow
PAK1STE20STE5kbrA(4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanoneHumanShow
PAK1STE20STE5kbrB(4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanoneHumanShow
PAK1STE20STE6b16An~4~-(5-cyclopropyl-1h-pyrazol-3-yl)-n~2~-[(1s)-1-(1h-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamineHumanShow
PAK1STE20STE6b16Bn~4~-(5-cyclopropyl-1h-pyrazol-3-yl)-n~2~-[(1s)-1-(1h-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamineHumanShow
PAK1STE20STE7vtoAA4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamideHumanShow
PAK1STE20STE7vtoAB4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamideHumanShow
PAK1STE20STE8x5zAA-HumanShow
PAK1STE20STE8x5zAB-HumanShow
PAK3STE20STE6fd3AAadenosine-5'-diphosphateHumanShow
PAK3STE20STE6fd3ABadenosine-5'-diphosphateHumanShow
PAK4STE20STE2bvaA-HumanShow
PAK4STE20STE2bvaB-HumanShow
PAK4STE20STE2cdzAAn2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamineHumanShow
PAK4STE20STE2cdzABn2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamineHumanShow
PAK4STE20STE2j0iAA-HumanShow
PAK4STE20STE2j0iAB-HumanShow
PAK4STE20STE2q0nAA-HumanShow
PAK4STE20STE2q0nAB-HumanShow
PAK4STE20STE2x4zApf-3758309HumanShow
PAK4STE20STE4appAAn-[6,6-dimethyl-5-[(2s)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamideHumanShow
PAK4STE20STE4appABn-[6,6-dimethyl-5-[(2s)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamideHumanShow
PAK4STE20STE4fieAphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4fieBphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4fifAAphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4fifABphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4fifBAphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4fifBBphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4figAphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4figBphosphoaminophosphonic acid-adenylate esterHumanShow
PAK4STE20STE4fihAA-HumanShow
PAK4STE20STE4fihAB-HumanShow
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