PDB-code
Browse kinase entries (page 240 of 282)
First 236 237 238 PreviousLast244 243 242 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | PRKACA (PKACa) | PKA | AGC | 8fe5 | A | 6-[(6p)-6-(1-methyl-1h-imidazol-5-yl)-2,3-dihydro-4h-1,4-thiazin-4-yl]-7,9-dihydro-8h-purin-8-one | Human | Show |  | |
| PRKACA (PKACa) | PKA | AGC | 8fec | A | 6-[(6p)-6-(4-bromo-1-methyl-1h-imidazol-5-yl)-2,3-dihydro-4h-1,4-thiazin-4-yl]-7h-purine | Human | Show | | |
| PRKACA (PKACa) | PKA | AGC | 8x5l | A | (2s)-2-(4-chlorophenyl)-2-hydroxy-2-[4-(1h-pyrazol-4-yl)phenyl]ethanaminium | Human | Show | | |
| PRKCA (PKCa) | PKC | AGC | 3iw4 | A | 3-(1h-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1h-pyrrole-2,5-dione | Human | Show | | |
| PRKCA (PKCa) | PKC | AGC | 3iw4 | B | 3-(1h-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1h-pyrrole-2,5-dione | Human | Show | | |
| PRKCA (PKCa) | PKC | AGC | 3iw4 | C | 3-(1h-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1h-pyrrole-2,5-dione | Human | Show | | |
| PRKCA (PKCa) | PKC | AGC | 4ra4 | A | (1r)-9-[(3s,4s)-1,3-dimethylpiperidin-4-yl]-8-(2-fluorophenyl)-1-methyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one | Human | Show | | |
| PRKCA (PKCa) | PKC | AGC | 8u37 | A | A | (6m)-3-amino-n-{4-[(3r,4s)-4-amino-3-methoxypiperidin-1-yl]pyridin-3-yl}-6-[3-(trifluoromethoxy)pyridin-2-yl]pyrazine-2-carboxamide | Human | Show | |
| PRKCA (PKCa) | PKC | AGC | 8u37 | A | B | (6m)-3-amino-n-{4-[(3r,4s)-4-amino-3-methoxypiperidin-1-yl]pyridin-3-yl}-6-[3-(trifluoromethoxy)pyridin-2-yl]pyrazine-2-carboxamide | Human | Show | |
| PRKCA (PKCa) | PKC | AGC | 8uak | A | A | (6m)-3-amino-n-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide | Human | Show | |
| PRKCA (PKCa) | PKC | AGC | 8uak | A | B | (6m)-3-amino-n-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide | Human | Show | |
| PRKCB (PKCb) | PKC | AGC | 2i0e | A | 3-{1-[3-(dimethylamino)propyl]-2-methyl-1h-indol-3-yl}-4-(2-methyl-1h-indol-3-yl)-1h-pyrrole-2,5-dione | Human | Show | | |
| PRKCB (PKCb) | PKC | AGC | 2i0e | B | 3-{1-[3-(dimethylamino)propyl]-2-methyl-1h-indol-3-yl}-4-(2-methyl-1h-indol-3-yl)-1h-pyrrole-2,5-dione | Human | Show | | |
| PRKCH (PKCh) | PKC | AGC | 3txo | A | 2-methyl-n~1~-[3-(pyridin-4-yl)-2,6-naphthyridin-1-yl]propane-1,2-diamine | Human | Show | | |
| PRKCH (PKCh) | PKC | AGC | 8fp1 | A | (3p)-3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)-7h-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile | Human | Show | | |
| PRKCH (PKCh) | PKC | AGC | 8fp3 | A | A | (3p)-3-{4-[(3r,5s)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | Human | Show | |
| PRKCH (PKCh) | PKC | AGC | 8fp3 | A | B | (3p)-3-{4-[(3r,5s)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | Human | Show | |
| Prkci (PKCi) | PKC | AGC | 4dc2 | A | A | adenine | Mouse | Show | |
| Prkci (PKCi) | PKC | AGC | 4dc2 | A | B | adenine | Mouse | Show | |
| PRKCI (PKCi) | PKC | AGC | 1zrz | A | 3-{1-[3-(dimethylamino)propyl]-1h-indol-3-yl}-4-(1h-indol-3-yl)-1h-pyrrole-2,5-dione | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 3a8w | A | adenosine-5'-triphosphate | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 3a8w | B | adenosine-5'-triphosphate | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 3a8x | A | - | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 3a8x | B | - | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 3zh8 | A | A | (2s)-3-phenyl-n~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 3zh8 | A | B | (2s)-3-phenyl-n~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 3zh8 | B | A | (2s)-3-phenyl-n~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 3zh8 | B | B | (2s)-3-phenyl-n~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 3zh8 | C | A | (2s)-3-phenyl-n~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 3zh8 | C | B | (2s)-3-phenyl-n~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5li1 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5li1 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5li9 | A | A | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5li9 | A | B | phosphomethylphosphonic acid adenylate ester | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5lih | A | A | adenosine-5'-diphosphate | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5lih | A | B | adenosine-5'-diphosphate | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5lih | B | A | adenosine-5'-diphosphate | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 5lih | B | B | adenosine-5'-diphosphate | Human | Show | |
| PRKCI (PKCi) | PKC | AGC | 6ilz | A | 2-amino-5-[3-(piperazin-1-yl)phenyl]-n-(pyridin-4-yl)pyridine-3-carboxamide | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 6ilz | C | 2-amino-5-[3-(piperazin-1-yl)phenyl]-n-(pyridin-4-yl)pyridine-3-carboxamide | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 6ilz | E | 2-amino-5-[3-(piperazin-1-yl)phenyl]-n-(pyridin-4-yl)pyridine-3-carboxamide | Human | Show | | |
| PRKCI (PKCi) | PKC | AGC | 6ilz | G | 2-amino-5-[3-(piperazin-1-yl)phenyl]-n-(pyridin-4-yl)pyridine-3-carboxamide | Human | Show | | |
| PRKCQ (PKCt) | PKC | AGC | 1xjd | A | staurosporine | Human | Show | | |
| PRKCQ (PKCt) | PKC | AGC | 2jed | A | 3-(8-dimethylaminomethyl-6,7,8,9-tetrahydro-pyrido[1,2-a]indol-10-yl)-4-(1-methyl-1h-indol-3-yl)-pyrrole-2,5-dione | Human | Show | | |
| PRKCQ (PKCt) | PKC | AGC | 2jed | B | 3-(8-dimethylaminomethyl-6,7,8,9-tetrahydro-pyrido[1,2-a]indol-10-yl)-4-(1-methyl-1h-indol-3-yl)-pyrrole-2,5-dione | Human | Show | | |
| PRKCQ (PKCt) | PKC | AGC | 4q9z | A | A | (1r)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one | Human | Show | |
| PRKCQ (PKCt) | PKC | AGC | 4q9z | A | B | (1r)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one | Human | Show | |
| PRKCQ (PKCt) | PKC | AGC | 4q9z | B | A | (1r)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one | Human | Show | |
| PRKCQ (PKCt) | PKC | AGC | 4q9z | B | B | (1r)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one | Human | Show | |
| PRKCQ (PKCt) | PKC | AGC | 4ra5 | A | A | (1r)-9-[(1,3-dimethylazetidin-3-yl)(methyl)amino]-1-methyl-8-phenyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one | Human | Show | |
