Search results (158 entries covering 43 PDB structures)

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#	Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	File
	ABL1	Abl	TK	6xr6	A	18	-	Human	Show
	ABL1	Abl	TK	6xr6	A	20	-	Human	Show
	ABL1	Abl	TK	6xr6	A	19	-	Human	Show
	ABL1	Abl	TK	6xrg	A	1	-	Human	Show
	ABL1	Abl	TK	6xrg	A	9	-	Human	Show
	ABL1	Abl	TK	6npu	A		4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6xrg	A	4	-	Human	Show
	ABL1	Abl	TK	8h7h	A		5-[3-(6-methoxyisoquinolin-7-yl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-~{n}-methyl-~{n}-prop-2-ynyl-pyridine-3-carboxamide	Human	Show
	ABL1	Abl	TK	2g2f	B		phosphothiophosphoric acid-adenylate ester	Human	Show
	ABL1	Abl	TK	4twp	A		axitinib	Human	Show
	ABL1	Abl	TK	7cc2	A		[4-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl]-2-methyl-phenyl]boronic acid	Human	Show
	ABL1	Abl	TK	7dt2	A		[4-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl]-2-methanoyl-5-methoxy-phenyl]boronic acid	Human	Show
	ABL1	Abl	TK	4zog	A		cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide	Human	Show
	ABL1	Abl	TK	5mo4	A	B	nilotinib	Human	Show
	ABL1	Abl	TK	6xr6	A	11	-	Human	Show
	ABL1	Abl	TK	6xr6	A	14	-	Human	Show
	ABL1	Abl	TK	6bl8	A	A	purvalanol b	Human	Show
	ABL1	Abl	TK	3pyy	A	A	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	2hz4	A		-	Human	Show
	ABL1	Abl	TK	4xey	A		n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	6xrg	A	3	-	Human	Show
	ABL1	Abl	TK	6xr6	A	3	-	Human	Show
	ABL1	Abl	TK	6xrg	A	11	-	Human	Show
	ABL1	Abl	TK	6xrg	A	12	-	Human	Show
	ABL1	Abl	TK	2hzi	A	A	6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	4wa9	A		axitinib	Human	Show
	ABL1	Abl	TK	4yc8	B		2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	6xr6	A	15	-	Human	Show
	ABL1	Abl	TK	6xr6	A	1	-	Human	Show
	ABL1	Abl	TK	2gqg	B	B	n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	6xrg	A	13	-	Human	Show
	ABL1	Abl	TK	6xrg	A	19	-	Human	Show
	ABL1	Abl	TK	6xrg	A	18	-	Human	Show
	ABL1	Abl	TK	7w7x	A		5-[5-(dimethylcarbamoyl)pyridin-3-yl]-3-(5-fluorosulfonyloxy-2-methoxy-phenyl)-1h-pyrrolo[2,3-b]pyridine	Human	Show
	ABL1	Abl	TK	6xr7	A	15	-	Human	Show
	ABL1	Abl	TK	6xr6	A	5	-	Human	Show
	ABL1	Abl	TK	7w7y	A		5-[3-(5-methanoyl-2-methoxy-4-oxidanyl-phenyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-~{n},~{n}-dimethyl-pyridine-3-carboxamide	Human	Show
	ABL1	Abl	TK	6xr7	A	5	-	Human	Show
	ABL1	Abl	TK	2hz4	B		1,2,3,4-tetrahydrogen-staurosporine	Human	Show
	ABL1	Abl	TK	2hz0	B	B	2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide	Human	Show
	ABL1	Abl	TK	6xr7	A	16	-	Human	Show
	ABL1	Abl	TK	3cs9	B	B	nilotinib	Human	Show
	ABL1	Abl	TK	2hz0	A	B	2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide	Human	Show
	ABL1	Abl	TK	6npv	B	A	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	2hyy	C		4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6npv	A	A	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	3pyy	B	B	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	3pyy	A	B	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6bl8	B	A	purvalanol b	Human	Show
	ABL1	Abl	TK	6xr7	A	8	-	Human	Show
	ABL1	Abl	TK	6xrg	A	8	-	Human	Show
	ABL1	Abl	TK	3ue4	B		4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile	Human	Show
	ABL1	Abl	TK	4wa9	B		axitinib	Human	Show
	ABL1	Abl	TK	3qrk	A		(3s)-6-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid	Human	Show
	ABL1	Abl	TK	6xr7	A	14	-	Human	Show
	ABL1	Abl	TK	6xr7	A	11	-	Human	Show
	ABL1	Abl	TK	6xr7	A	1	-	Human	Show
	ABL1	Abl	TK	6xrg	A	7	-	Human	Show
	ABL1	Abl	TK	6npe	B	A	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	2hzi	A	B	6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	2g2f	A		-	Human	Show
	ABL1	Abl	TK	6xr6	A	13	-	Human	Show
	ABL1	Abl	TK	6xr7	A	17	-	Human	Show
	ABL1	Abl	TK	4xey	B		n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	6xr6	A	12	-	Human	Show
	ABL1	Abl	TK	3qri	B	A	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	2hyy	B		4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	2hzi	B	A	6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	6xr6	A	17	-	Human	Show
	ABL1	Abl	TK	6npv	B	B	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	3qri	A	A	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	6xrg	A	14	-	Human	Show
	ABL1	Abl	TK	6bl8	B	B	purvalanol b	Human	Show
	ABL1	Abl	TK	2v7a	A		n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide	Human	Show
	ABL1	Abl	TK	6xr6	A	2	-	Human	Show
	ABL1	Abl	TK	2g2i	B		adenosine-5'-diphosphate	Human	Show
	ABL1	Abl	TK	2hiw	A		7-amino-1-methyl-3-(2-methyl-5-{[3-(trifluoromethyl)benzoyl]amino}phenyl)-2-oxo-2,3-dihydropyrimido[4,5-d]pyrimidin-1-ium	Human	Show
	ABL1	Abl	TK	6xr7	A	19	-	Human	Show
	ABL1	Abl	TK	6npe	B	B	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6xr6	A	7	-	Human	Show
	ABL1	Abl	TK	3qrj	B	A	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	2hz4	C		-	Human	Show
	ABL1	Abl	TK	3cs9	C	A	nilotinib	Human	Show
	ABL1	Abl	TK	2g1t	C		-	Human	Show
	ABL1	Abl	TK	6xr7	A	2	-	Human	Show
	ABL1	Abl	TK	2hyy	A		4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6xrg	A	5	-	Human	Show
	ABL1	Abl	TK	3ue4	A		4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile	Human	Show
	ABL1	Abl	TK	6xr6	A	9	-	Human	Show
	ABL1	Abl	TK	2f4j	A		cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide	Human	Show
	ABL1	Abl	TK	3pyy	B	A	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	3cs9	C	B	nilotinib	Human	Show
	ABL1	Abl	TK	2g2h	B		6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	3cs9	D	B	nilotinib	Human	Show
	ABL1	Abl	TK	6xrg	A	16	-	Human	Show
	ABL1	Abl	TK	6xrg	A	20	-	Human	Show
	ABL1	Abl	TK	6xrg	A	10	-	Human	Show
	ABL1	Abl	TK	4twp	B		axitinib	Human	Show
	ABL1	Abl	TK	2g1t	B		-	Human	Show
	ABL1	Abl	TK	5hu9	A	B	4-[(4-methylpiperazin-1-yl)methyl]-n-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide	Human	Show
	ABL1	Abl	TK	2hz0	A	A	2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide	Human	Show
	ABL1	Abl	TK	6xr7	A	4	-	Human	Show
	ABL1	Abl	TK	6xrg	A	2	-	Human	Show
	ABL1	Abl	TK	4zog	B		cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide	Human	Show
	ABL1	Abl	TK	6xr6	A	6	-	Human	Show
	ABL1	Abl	TK	3cs9	A	A	nilotinib	Human	Show
	ABL1	Abl	TK	6xr6	A	4	-	Human	Show
	ABL1	Abl	TK	5hu9	A	A	4-[(4-methylpiperazin-1-yl)methyl]-n-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide	Human	Show
	ABL1	Abl	TK	2e2b	A		n-[3-(4,5'-bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide	Human	Show
	ABL1	Abl	TK	6npu	B		4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	5mo4	A	A	nilotinib	Human	Show
	ABL1	Abl	TK	6xr7	A	3	-	Human	Show
	ABL1	Abl	TK	2hyy	D		4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6xr6	A	10	-	Human	Show
	ABL1	Abl	TK	7n9g	A		n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	4yc8	A		2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	3qrj	A	B	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	6xr6	A	16	-	Human	Show
	ABL1	Abl	TK	6xr7	A	10	-	Human	Show
	ABL1	Abl	TK	3qrj	A	A	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	6npe	A	B	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	2gqg	A	A	n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	6bl8	A	B	purvalanol b	Human	Show
	ABL1	Abl	TK	6xr6	A	8	-	Human	Show
	ABL1	Abl	TK	6npv	A	B	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6xr7	A	7	-	Human	Show
	ABL1	Abl	TK	3qrj	B	B	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	6xr7	A	18	-	Human	Show
	ABL1	Abl	TK	2g2i	A		adenosine-5'-diphosphate	Human	Show
	ABL1	Abl	TK	2gqg	B	A	n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	1opl	B		6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	2g1t	A		-	Human	Show
	ABL1	Abl	TK	2hzi	B	B	6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	6npe	A	A	4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Human	Show
	ABL1	Abl	TK	6xr7	A	13	-	Human	Show
	ABL1	Abl	TK	6xrg	A	15	-	Human	Show
	ABL1	Abl	TK	8h7f	A		1-[6-(6-methoxyisoquinolin-7-yl)-1,3-benzothiazol-2-yl]-3-(2-oxidanylideneethyl)urea	Human	Show
	ABL1	Abl	TK	3cs9	A	B	nilotinib	Human	Show
	ABL1	Abl	TK	1opl	A		6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	2fo0	A		6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	6xr7	A	20	-	Human	Show
	ABL1	Abl	TK	6xr7	A	9	-	Human	Show
	ABL1	Abl	TK	3cs9	B	A	nilotinib	Human	Show
	ABL1	Abl	TK	6xrg	A	17	-	Human	Show
	ABL1	Abl	TK	3qri	A	B	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	3qri	B	B	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	Show
	ABL1	Abl	TK	2hz0	B	A	2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide	Human	Show
	ABL1	Abl	TK	2gqg	A	B	n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide	Human	Show
	ABL1	Abl	TK	8ssn	A		6,7-dimethoxy-n-(4-phenoxyphenyl)quinazolin-4-amine	Human	Show
	ABL1	Abl	TK	6xr7	A	12	-	Human	Show
	ABL1	Abl	TK	2e2b	B		n-[3-(4,5'-bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide	Human	Show
	ABL1	Abl	TK	3cs9	D	A	nilotinib	Human	Show
	ABL1	Abl	TK	6xrg	A	6	-	Human	Show
	ABL1	Abl	TK	2g2h	A		6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	ABL1	Abl	TK	2g1t	D		-	Human	Show
	ABL1	Abl	TK	6xr7	A	6	-	Human	Show
	ABL1	Abl	TK	2hiw	B		7-amino-1-methyl-3-(2-methyl-5-{[3-(trifluoromethyl)benzoyl]amino}phenyl)-2-oxo-2,3-dihydropyrimido[4,5-d]pyrimidin-1-ium	Human	Show
	ABL1	Abl	TK	2v7a	B		n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide	Human	Show

Division of Medicinal Chemistry - Vrije Universiteit Amsterdam